🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Baltimore's drop in homicides - 23% since last year and a staggering 40% from two years ago - should be a national story. Mayor Scott's Group Violence Reduction Strategy, which prioritizes resources to those most at risk and community engagement, should be studied and replicated.

It is very sad to learn that Martin Karplus passed away on Dec 28 at age 94. He was a scholar and pioneering chemical physicist with great contributions in many areas including molecular dynamics. We interacted many times starting from my graduate time at Harvard. His legacy is

The first preprint of 2025! Together with @khorms, Vanja (Ivan Kulakovskiy), & our amazing team, we are excited to share PARADE: an AI framework for designing mRNA UTRs with enhanced cell-type specificity & stability. biorxiv.org/content/10.110…

Published in PNAS: T. Moosmayer, K.A. Kiszka et al. (2024) "#MINFLUX fluorescence nanoscopy in biological tissue". Open access at pnas.org/doi/abs/10.107… including PSD95, presynaptic VGlut1 clustering and AMPAR clustering at the post-synapse MPI for Multidisciplinary Sciences Max Planck Institute for Medical Research

Novel fluorescent RGEPO sensors enable real-time visualization of both intracellular and extracellular potassium ion (K⁺) fluctuations in live tissues, allowing potassium dynamics to be imaged during seizures in mice for the first time biorxiv.org/content/10.110…

The HPV vaccine prevents 90% of cases of cercical cancer This is one of great medical achievements of our time! bbc.co.uk/news/articles/…

Maybe useful for those wanting to infer action potentials from calcium imaging: Sam Wang's lab just posted to biorxiv "Precise calcium-to-spike inference using biophysical generative models" "jGCaMP8f showed a use-dependent slowing of fluorescence responses ...

The first successful use of 2P voltage imaging in vivo with rhodopsin-based GEVI indicators🥳 Photophysics-informed two-photon voltage imaging using FRET-opsin voltage indicators | Science Advances science.org/doi/full/10.11…

🔬peeps! I am delighted to finally publish my code for controlling a spatial light modulator (SLM) to perform adaptive optics & to sculpt the vortex beams for STED & MINFLUX microscopy - complete w graphical user interface for easy use! github.com/wiebkejahr/slm… Short user manual🧵

Microscopy Nodes: versatile 3D microscopy visualization with Blender Oane Gros, Chandni Bhickta, Granita Lokaj, Yannick Schwab, Simone Köhler and Niccolò Banterle biorxiv.org/content/early/…

I'd like to draw your attention to this truly excellent paper from the Taraska lab on cryoET of plasma membrane associated proteins. Everyone who is thinking about probes in the cryoET space should also see what they could do with ferritag (fig 6) nature.com/articles/s4146…

Our spatial multi-omics technology that co-profiles five modalities is now published in Nature Methods Nature Methods! Huge thanks to Marek Bartosovic, Mingyao Li, and my amazing team, including postdoc Pengfei_Guo and PhD student Liran Mao! nature.com/articles/s4159…

🧵Prepint! Optimizing Multifunctional Fluorescent Ligands for Intracellular Labeling |tinyurl.com/3n55hvsc. With Jason Vevea @TheChapmanLab David Solecki (pronounced so_lets_ki 😉), we combined dye chemistry, HaloTag, microscopy and cell biology to make protein purification and manipulation tools.

#BIA users / developers / fans don't miss the #AI4Life GloBIAS webinar series starting already in February! 👇👇

🚨🚨 MEGA JOB ALERT 🚨🚨 Independent Group Leader Positions in Computational Biology Human Technopole! Are you ready to start your own lab? Do you know someone who is? Repost this + share with everyone who might want to know about it. Thanks!!! 🙏 More details below... 🧵 1/3

If you are interested by building or applying new microscopes around single molecule, FLIM, in depth imaging, live-cell+ SMLM…, we are opening new post-doc positions for various backgrounds funded by ERC grant (flexible start). shorturl.at/fYNij shorturl.at/gDQkz

Optical nanoscopy, but without the OFF...! Published in Nature Physics by T.A. Hensel, J.O. Wirth, O.L. Schwarz & S.W. Hell. Check it out with open access at nature.com/articles/s4156… MPI for Multidisciplinary Sciences Max Planck Institute for Medical Research #Imaging #Optics #Waves #Microscopy

Out today from the Singh and Way labs! Pycytominer is a user-friendly, open-source Python package that carries out key bioinformatics steps in image-based profiling. nature.com/articles/s4159…

We're hiring a postdoc for an exciting joint project with KlenermanLab and the Davis Lab, focusing on Super-resolution Microscopy of Immune Cells at Cambridge. Happy to chat informally, feel free to reach out! 📢 Please share! More details here: jobs.cam.ac.uk/job/50547/

🔬Check out #FACED 2.0 for high-throughput, in vivo 2D/3D two-photon fluorescence microscopy led by Na Ji. Excited to be part of it and see how #FACED is further pushed its limit!! 🧠Continuous 3D imaging of cerebral blood flow within millimeter-scaled volumes in the cortex of