A dedicated issue of Science Translational Medicine on #LongCovid —Sex-specific differences, with perspective by Prof. Akiko Iwasaki and Julio Silva —Insights for therapies Andrea Cox —Deconvoluting "Osler's Web" Michael Peluso, MD Steven Deeks Maureen Hanson Sharon Saydah —+RECOVER Trial,

NEW: Govt has published outcome of consultation on ME and chronic fatigue syndrome. Delivery plan due in March 2025 too. After delays under the last govt, these are serious steps forward. Many thanks to minister Andrew Gwynne MP. gov.uk/government/con…

Listen to the latest episode of our podcast 'EDI Chronicles at Brain Sciences'. In this episode, we speak to Dr Rikesh Rajani, Senior Research Fellow and member of the Disability Equity Committee about his experience of being an academic with #LongCOVID. bit.ly/3PvliVj

Delighted to announce Rikesh Rajani as the first Group Leader to join our flagship vascular dementia research centre with British Heart Foundation🎉👏 The Rajani Lab will investigate how the protective myelin sheath around brain cells is damaged in small vessel disease👉buff.ly/4hIGaVM

Excited to share that I'll soon be moving back to Edinburgh to start my own lab, as part of the BHF-UK DRI Centre for Vascular Dementia Research! The Rajani Lab will be recruiting soon, so keep your eyes peeled...

New research led by Marc Aurel Busche has found that tau specifically disrupts a certain type of electrical activity in the hippocampus in Alzheimer's🧠 The findings unlock a key piece of the puzzle in understanding how toxic tau drives memory problems👏👉buff.ly/yx8Rdk6

Delighted to have played a part in this work, now out in Cell, where we show how soluble high molecular weight tau from Alzheimer’s brain suppresses burst firing in hippocampal neurons.

🧠 Paper alert! My scientific labour of love from my time at the UK Dementia Research Institute at UCL is now out in Neuron ! Deep-layer 5/6 PV interneurons show early dysfunction in Alzheimer's models in vivo, tied to NPTX2 and GluA4 loss. 🔗 cell.com/neuron/fulltex… 🧵Thread below ⬇️

More great work from the Busche Lab that I’m glad to have played a part in. Now out in Neuron, we show that the earliest neuronal dysfunction in Alzheimer’s models is seen in parvalbumin interneurons in deep cortical layers.

Hiring! We're looking for a postdoc to join my lab at the UK Dementia Research Institute @UCL. We’re investigating neuronal and circuit dysfunction in Alzheimer's, and developing innovative new treatments. Apply here👇 shorturl.at/LpCAq #Neuroscience #Alzheimers #Postdoc #Hiring #Dementia

Great to see this excellent study that I contributed to now out in Cell Reports. We show the key role the APP family plays in regulating synaptic NMDA receptors and spontaneous neuronal activity.

🧠How do brain circuits fail in early Alzheimer's disease? 🧠 Join Dr Marc Aurel Busche for the next research webinar in our 'Rethinking neurodegeneration' series, taking place 4-5pm (BST), Thurs 24 July 🗓️ During this fascinating talk and Q&A, Dr Busche will present

The Rajani Lab is hiring! We are looking for a postdoc to join us at UK Dementia Research Institute The University of Edinburgh to investigate neuronal activity and white matter changes in vascular dementia. Apply here 👇 bit.ly/44AFJHx

Congratulations Rikesh! Definitely consider applying to this exciting project and new lab :)

The UK Dementia Research Institute at University of Edinburgh is looking for a postdoctoral Research Fellow to join the Rajani Lab as part of the new national BHF-UK DRI Centre for Vascular Dementia Research. Closing date: 13th August dementiaresearcher.nihr.ac.uk/job/uk-dementi…

Wonderful to see @Rikesh_Rajani recruiting for his new lab! He’s a fantastic scientist and a great colleague - I highly recommend applying.

Delighted our latest research is featured on the cover of Neuron today! We reveal an early vulnerability in Alzheimer's disease: deep cortical layers (5/6) and their fast-spiking interneurons. Dysfunction is caused by loss of NPTX2 and importantly is reversible.

Just over a week left to apply for this position in our lab!