Excited to share our latest work in Immunity led by our own Siyu Sun The Halvorsen Center for Computational Oncology Memorial Sloan Kettering Cancer Center, who tried to assemble the puzzle of how cancer cells and cancer-immune interactions co-evolve with the retrotransposons of the #DarkGenome! With Eunae You, Sasha Solovyov,

Several years in the making (and aging), Xueqian Zhuang 's study on aging is out today nature. She finds, surprisingly, that aging suppresses tumorigenesis and stemness in the lung by promoting a functional iron insufficiency in the alveolar epithelium. nature.com/articles/s4158…

A culmination of ~5 years of work, today our work on biallelic alterations across tumor suppressor genes is published in Cell. With Mark Zucker, Maria Perry, and Chai Bandlamudi cell.com/cell/fulltext/…

New in nature: ASPIRE awardee Andrea Ventura (Andrea Ventura) shares a new method to engineer and study gene amplifications mediated by extrachromosomal DNAs (ecDNAs). 🧬 Memorial Sloan Kettering Cancer Center #CancerResearch nature.com/articles/s4158…

Groundbreaking new work from Andrea Ventura and colleagues! These findings and these systems will power the ecDNA field for years to come.

🥳Review paper online: Modern biology of extrachromosomal DNA: A decade-long voyage of discovery👏You'll find modern ecDNA biology uncovered over the last ten years👍Kudos to my trainees who put everything together❤️Thank Cancer Grand Challenges for support! nature.com/articles/s4142…

On behalf of Kentsis Research Group, we invite the submission of #abstracts for the 2025 Robert Steel Symposium in Developmental Oncology Memorial Sloan Kettering Cancer Center. Abstracts will be selected for live oral presentations during this year's exciting event, taking place May 19–20 in New York City.

Most excited to see our study presenting the mechanism driving ~50% of osteosarcomas (LTA #chromothripsis) out in Cell! How does the final version differ from the preprint? x.com/isidrolauscher… Buckle up!! -tons of new exciting results ahead! 👇👇

I am extremely proud to see our work about Hepatitis B now published in Cell. From basic research to identifying the key step of infection & a potential first drug for curing this devastating disease. This has been an incredible journey.🧵 cell.com/cell/fulltext/…

New book out: Developmental Oncology: Principles and Therapy of Cancers of Children and Young Adults ☛ alexkentsis.net/book-developme…

📢 [Live Webinar] Modern Biology of ecDNA in Cancer Through the Lens of #3DGenomics with Dr. Sihan Wu 吴思涵 Discover how 3D genomic technologies are transforming our understanding of #ecDNA in small cell lung cancer (SCLC). Plus, learn how ecDNA drives tumor evolution, therapy

A new KRG study led by Sumiko Takao et al Nature Communications uncovers how epigenetic mechanisms control human leukemia stem cells (LSCs) that fuel therapy resistance in AML. nature.com/articles/s4146… #Leukemia #Epigenetics

Fantastic new work from Jane Xu and the Viny lab The Viny Lab! It’s been wonderful to be part of this collaboration and I’m excited to see where Jane et al take this next 🚀

Truly groundbreaking research with immediate benefits to patients from Lorenz Viviane Tabar Memorial Sloan Kettering Cancer Center and colleagues at BlueRock Therapeutics

Excited to share our paper out today in Cell Press discovering RNA mis-splicing derived neoantigens & their cognate T cell receptors (TCRs) as well as characterization of endogenous neoantigen T cells in leukemia patients. authors.elsevier.com/sd/article/S00…

.Michael Berger, David B. Solit, MD, Marc Ladanyi, and the MSK-Impact team accept the AACR Team Science Award for developing and implementing a groundbreaking next-generation sequencing platform which has enabled the comprehensive molecular characterization of over 125,000 tumors. #AACR25

Excited to announce our annual New York City Edward P. Evans MDS Centers Symposium across Memorial Sloan Kettering Cancer Center & Columbia University on Monday, July 14, 2025. This year to be held at Memorial Sloan Kettering Cancer Center. See this flyer below and register here: forms.fillout.com/t/1wX3dGmym4us

In a new study published in Cell Press, researchers from MSK and Fred Hutch Cancer Center show that it may be possible to develop an #immunotherapy-based approach for #AcuteMyeloidLeukemia and #myelodysplastic syndrome. “This is a potential breakthrough,” says Dr. Omar Abdel-Wahab. “We’re

Big day for the David lab! 🎉 Our Molecular Cell paper is out today- huge congrats to first authors Ifé Akano & Jake Hebert for leading this beautiful study uncovering SMARCA3 as a novel H3 E3 ligase that shapes heterochromatin regulation in colorectal cancer 🤩

This was an incredible collaboration! I didn't expect we'd find such an intricate link between tumor cell invasion, mechanical stress, cell state switching, and chromatin state. Major kudos to richard white, Miranda Hunter, and all colleagues Memorial Sloan Kettering Cancer Center and University of Oxford