🌐 Exciting development in HCC research! Building on our oncofetal ecosystem discovery, this team effort led by Ziyi Li, with @realFlorentGinhoux, Pierce Chow, Jacob George, Rhea Pai, Saurabh Gupta, Jennifer Currenti, and others, is a game-changer. It opens doors for using #oncofetal ecosystems as

Ankur Sharma Nature Cancer Harry Perkins Institute Curtin University A*STAR Research Gustave Roussy The Westmead Institute for Medical Research An amazing collaboration, started few years ago… we found first endothelial cells and macrophages exhibiting such fetal reprogramming in HCC… fibroblasts had to be there also as essential element of tissue blocks! Thanks to Dr. Ziyi Li that lead the effort! Congratulations

Integrate Stereo-seq's 'true single-cell resolution', scientists delineated specific cell subsets involved in hepatocellular carcinoma (HCC) relapse and response to immunotherapy. Learn more go.nature.com/3NNG9To Ankur Sharma

@realFlorentGinhoux Rhea Pai Saurabh Gupta Jennifer Currenti Here is full text access link rdcu.be/duW2H

Starting the new year with this beautiful work published in Nature Cancer !! It highlights how oncofetal cells may be linked to post-surgery relapse. Thrilled to be part of this study led by Ziyi Li, thanks to my mentor Ankur Sharma & our collaborators

Excited to share our work out in Nature Cancer. We uncover the role of HCC #oncofetal niche in EMT, relapse, and IO response, marking a significant step towards using OF signatures for patient stratification. OncoFetal Ecosystem Lab Harry Perkins Institute Curtin University Ankur Sharma

A new study by Ankur Sharma showcases #BGI’s Stereo-seq's prowess in achieving 'true single-cell resolution.' This breakthrough has enabled the detailed mapping of cell types for understanding hepatocellular carcinoma relapse and response to immunotherapy. bit.ly/3twLLe5

🎇NEW YEAR, NEW PAPERS – “Presence of onco-fetal neighborhoods in hepatocellular carcinoma is associated with relapse and response to immunotherapy” by @realFlorentGinhoux Ankur Sharma & Co. Check it out👇 nature.com/articles/s4301… rdcu.be/dvEIM

Congrats on a beautiful article by Kelsey Woodruff in our lab - out today in nature. Organize your –80 °C freezer to save time and prevent frozen fingertips nature.com/articles/d4158… New Organizō freezer inventory template just dropped: organizolife.com/downloads #TheLabEdit

Congratulations to all successful candidates! Specially Jennifer Currenti who joined OncoFetal Ecosystem Lab 2 years ago and have made significant contributions in understanding role of T-cells in HCC immunotherapy Cure Cancer

Congrats Jennifer Currenti for your Cure Cancer grant to advance research into developing a blood test to identify patients who could respond to #Immunotherapy treatments for hepatocellular carcinoma. perkins.org.au/predicting-imm…

Congratulations Archita Mishra for being selected as a Sydney Horizon Fellow University of Sydney wishing you best on this exciting journey ahead #HorizonFellowship #earlylife #microbiome #immunity

So excited and humbled to be selected as a Sydney Horizon Fellow University of Sydney and be part of this amazing cohort of scientists..!! #ECR #immunology #childhealth #microbiome #immunepriming

Every PIs nightmare... a -80 freezer failure after just 2.5 years. Thankfully, we were there when it happened, all our samples are safe and didn't warm above -65 during transfer to a backup. So what have I learned from this?

Wanna do standard 3’, 5’ etc ⁦⁦10x Genomics⁩ applications-seq without stress? No worries! FixNCut it baby! Laura Jiménez Gracia YOU are the best! Holger Heyn Dr. Jasmine Plummer 👩🏻‍🔬🧬🇨🇦🇺🇸 CNAG ⁦Omniscope⁩ genomebiology.biomedcentral.com/articles/10.11…

Symbiotic Symphony: our review on why catching #host #Microbiome dialogues in its true space matters! The key to #immunepriming & #PrecisionMedicine Kudos to Soumi Chatterjee for the smarts & grit in piecing together this puzzle 🔎🤩 #SpatialTranscriptomics authors.elsevier.com/a/1is5a3si8Pym…

Very excited to co-lead @NHMRC 2023 Clinical Trial & Cohort Grant (6M AUD) with Jacob George for the clinical trial (DEFINERx050) and cohort (PRECISION). We will establish a pan-national HCC cohort across 5 states & 13 clinical sites to evaluate #oncofetal score and other

Happy for Perkins to host Luciano Martelotto 🛠🧬💻🇦🇺 for an overview of spatial omics technologies

Just before the summer break! Very proud and excited to share our latest work on tumor macrophage ontogeny ! Spatial temporal regulation of TAM development revealed using time stamping approaches! Ms4a3 Creert2 is a gem! science.org/doi/10.1126/sc…, congratulations to the team!

Beautiful work in Science Immunology on ‘Spatio-temporal’ dynamics of tumour associated macrophage in cancer by Garett Dunsmore @realFlorentGinhoux Great to collaborate with this wonderful team on important aspect of TAMs with implications therapeutic intervention science.org/doi/10.1126/sc…