A high-throughput platform for biophysical antibody developability assessment to enable AI/ML model training 1. PROPHET-Ab is a high-throughput platform developed by Ginkgo Bioworks to systematically assess antibody developability and generate ML-ready datasets at

Great new resource for anyone working on antibody CMC, developability, or discovery. New preprint out today from Ginkgo that benchmarks 246 therapeutic IgGs across 10 developability assays. The resulting dataset is ML-ready and publicly available. If you're thinking about early

📷 Preprint: biorxiv.org/content/10.110… 📷 Dataset: datapoints.ginkgo.bio/antibody-devel… 📷 Platform overview: datapoints.ginkgo.bio/antibody-devel…

Excited to share Ginkgo Bioworks 's third functional genomics dataset release, GDPx3 - a cell painting dataset featuring 3 primary cell lines and the A549 human lung adenocarcinoma cell line. 220 GB of imaging data, with additional data available to license:

Another day, another free data set! Awesome cell painting data on 46 compounds in dose response across 3 primary human cell types + A549s. Download the dataset below! 👇

GDPx3 features comprehensive morphological profiles for 46 compounds! What makes this dataset uniquely valuable? It provides critical dose-response data across three PRIMARY human cell types with two timepoints (24 hrs, 48 hrs), plus a widely used cell line. 🔬🦠 Aortic Smooth

Executive order out yesterday taking a firm stance against risky gain of function research and the development of biological weapons. If we want to ensure that other countries aren't developing biological weapons we can't just trust them -- we need to be monitoring for it.

Securing the Biological Frontier: securingbiology.com EO Improving the Safety and Security of Biological Research: whitehouse.gov/presidential-a…

My colleagues Joshua Moller & Porfirio Quintero Ginkgo Bioworks are presenting our poster on guided discrete diffusion for antibody developability tomorrow at PEGS Boston 🧵 (1/4)

We guide antibodies towards low hydrophobicity and polyreactivity using simple oracles trained on 250 antibodies from our latest preprint (biorxiv.org/content/10.110…) (2/4)

We successfully guide towards these properties while maintaining high naturalness (likelihood) scores under other models such as AbLang2. We've found SVDD (arxiv.org/abs/2408.08252…) to work better than other discrete diffusion guidance approaches. (3/4)

Excited to expand this further with bigger datasets! They're presenting at the following times: Thursday May 15 10:30-11:15AM 12:25-1:55PM Poster session C Poster hashtag #C044 Feel free to reach out to [email protected] if you want to know more! (4/4)

Thank you Oliver Varhelyi for your visit to Ginkgo Bioworks to talk about how we can ensure that everyone can reap the benefits of biotechnology while safeguarding people, livestock and crops from emerging biothreats.

Great article from Vox on biological weapons and how to defend against them - with commentary from Matthew F. McKnight who leads biodefense work at Ginkgo Bioworks. We need to be proactive about this in USG so we aren’t defenseless. vox.com/future-perfect…

We’re excited to launch a powerful new capability at Ginkgo Datapoints: high-throughput, low-cost ADME profiling—optimized for machine learning from day one. Whether you’re prioritizing small molecules or training predictive models, early access to rich ADME data can

Cell-free protein synthesis systems, optimized at Ginkgo and now available to you! Ginkgo has been using cell-fee protein synthesis systems in house for years, and we’re now making our E. coli system available to outside users! We’ve optimized it for: • High production from

⭕ Circular RNA developed at Ginkgo. Validated by pharma. Available to you today! We're excited to launch CIRQ, a new circular RNA R&D service from Ginkgo, designed to solve the persistent challenges with traditional mRNA—stability, immunogenicity, and scalable manufacturing.

Ginkgo Automation is proud to support the Environmental Molecular Sciences Laboratory (EMSL) at Pacific Northwest National Laboratory (PNNL) in accelerating microbial research to power the bioeconomy. Through this collaboration, Ginkgo will deploy flexible, modular automation

Ginkgo's modular automation has been on a tear lately! We are able to install our modular automation INSIDE a large anaerobic chamber for Pacific Northwest National Laboratory (PNNL)! Really excited for the scale of experimentation they will be able to do to advance science

Ginkgo Datapoints is excited to announce a transformative strategic partnership with Tangible Scientific and Inductive Bio. The partnership is aimed at significantly accelerating drug discovery through the seamless integration of AI-driven lab-in-the-loop workflows. This