Thrilled to see our recent work in nature . Here we describe how ILC2s regulates tissue localized vs systemic immunity. MRC Laboratory of Molecular Biology , Wellcome, UK Research and Innovation nature.com/articles/s4158…

We have an exciting new PhD project available in our lab! It will be studying the impact of environmental pollutants on allergic sensitisation through the skin. If interested, have a look below. Deadline end of August. findaphd.com/phds/project/a…

We describe that Il-9 and Il-21 have partially overlapping and synergistic effects in asthma. Check out doi.org/10.1016/j.jaci… Nice collab with Benjamin Medoff in MGH and argenx Revive Il-9 !

Applications are open for postoctoral position in my lab! The role will be a clinical project on understanding how the maternal immune system can contribute to the development of fetal congenital heart diseases. Deadline 9th of September. jobs.ac.uk/job/DJG019/pos…

If you are interested in lung inflammation during viral respiratory infections have a look at the latest paper from our team. Great work by Amber Owen and colleagues. NHLI mucosalimmunology.org/article/S1933-…

It’s #FluorescentFriday and we’re back with some stunning images fresh from the lab!🔬 This week, immune cells lighting up the #lung parenchyma from Ciara! Zooming in to catch those cell/cell interaction 🎨Colour Code 🔵Neutrophil 🟡CD45 🟢Mast Cell Granule 🟣CD18 NHLI

We are hiring again! Lecturer/Senior Lecturer in Immunology, looking for great people just starting their labs or a bit more established to join the fantastic immunology environment in Manchester. Immunology, Immunity to Infection, Respiratory Med Lydia Becker Institute jobs.manchester.ac.uk/Job/JobDetail?…

"It's hugely exciting that we now have a vaccine that lasts for this important condition which affects both babies and older adults" - Professor Peter Openshaw on the new Respiratory Syncytial Virus (RSV) vaccine, which is being rolled out for the first time 💉

Why are poor respiratory outcomes so common after #LungResection? Researchers show the procedure triggers #eosinophil maturation, activation, and #inflammation that damages lung tissue in mice, which can be targeted with a NOS inhibitor. Science Translational Medicine scim.ag/8fk

New paper out nature - why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? sex chromosomes or hormones? Here we studied adaptation of human immune systems to gender-affirming

In our new paper out today nature.com/articles/s4158…, we started with a simple hypothesis - inspired by work on IL-4/IL-13 from Brian S. Kim - that an innate immune cell might control sensory neuronal detection of allergens via a secreted factor. (1/11)

New #FluorescenceFriday with this week one of the first image of Ekhlas imaging #heart microvasculature looking for #mastcells 🔬🤩🫀 🎨Colour Code 🔵 CD31 (endothelial cells) 🟢 Mast Cells NHLI Lloyd Lab NHLI BHFCoREImperial

Excited to present next week at #LondonInfectImmun at The Crick, where I'll be discussing our latest findings on the airway wall and how asthma disrupts its spatial organisation. Looking forward to sharing our progress! Lloyd Lab NHLI NHLI NIHR Imperial BRC

Don’t miss Frontiers in Bioimaging 2024 in Oxford! Dive into groundbreaking research with incredible speakers: Virginie Uhlmann, Marine Laporte, Alberto Elosegui-Artola, Mark Leake & more 🔬 Join for insights that could shape the future of bioimaging RMS Stefania Marcotti

Pericytes in the brain & heart: functional roles & response to ischaemia & reperfusion "pericyte-mediated capillary constriction plays a key role in restricting blood flow after ischaemia" Also in #SkeletalMuscle, Kidney or Diabetic Islets?😆 Turgay Dalkara & David Attwell labs

Hold on to your hats! The winners of the 2024 #NikonSmallWorldInMotion competition have finally been revealed, and they're sure to blow you away. View the full video gallery here: bit.ly/47t3L8A

Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia. Congrats Dave Attwell, Nils Korte and team! 🤩 nature.com/articles/s4159…

We had a fantastic time at The London Infection & Immunity Symposium 2024 The Crick. Two days of inspiring science and stimulating discussion! Superb talks from Clare and Régis Joulia (Joulia Lab). Thank you to the organisers for such an enjoyable symposium.

Our first try of whole lung lobe using light-sheet microscopy for this week #FluorescentFriday 🔬🫁 The image is stunning, and we're just getting started. Stay tuned for more soon! 🤩 🎨Colour Code 🔵 Mast cell 🟢 Vasculature 🟣 Smooth muscle NHLI Imperial College London

New #FluorescentFriday alert! We are diving into uncharted territory with kidney microcirculation and looking for mast cells! 🔬👀 🎨 Colour Code 🔵 Vasculature (CD31) 🟣 Mast Cells (avidin) NHLI