Recurrence Patterns of Esophageal Adenocarcinoma in the ESOPEC Trial Comparing Perioperative CTx With Preoperative Chemoradiotherapy Journal of Clinical Oncology doi.org/10.1200/JCO-25… 👉similar locoregional recurrence 👉less Distant recurrence with FLOT 🧐FLOT improved OS through better systemic

The key question is in those who fail FLOT and surgery, where is the failure? 43/89=48.3% have locoregional failure. Lots of room here for improvement Dr. Nina Niu Sanford Krishan Jethwa

After the provocative editorial by Ian Tannock et al. against the use of adjuvant CDK4/6i (ascopubs.org/doi/abs/10.120…) a reply in defense of adjuvant CDK4/6i is now out in Journal of Clinical Oncology, showing treatment effect across multiple censoring scenarios 👇🏻 ascopubs.org/doi/10.1200/JC… OncoAlert

Summary of combination therapy in advanced RCC. Hard to compare phase II trials but clearly multiple options are emerging. #uromigoslive Uromigos

Summary of all the PD(L)1x VEGF bispecifics in development Uromigos #uromigoslive

Distinct clinicopathological and survival profiles of CLDN18.2 and PD-L1 expression in advanced gastric cancer and gastroesophageal junction adenocarcinoma - ESMO Gastrointestinal Oncology esmogastro.org/article/S2949-…

Increased risk of early-onset gastric cancer among young adults age 20–49 years with diabetes: a nationwide cohort study - eClinicalMedicine thelancet.com/journals/eclin…

Staging laparoscopy for gastric cancer: European consensus ➡️doi.org/10.1093/bjs/zn… 🎯 Establish expert consensus on the timing and methodology of staging laparoscopy in gastric cancer within a multinational European context. 🧮These data provide practical, Europe-wide

Liver Transplant for Upfront Unresectable Colorectal Metastases ⁦JAMA Surgery⁩ jamanetwork.com/journals/jamas…

This #LungCancerAwarenessMonth, we celebrate progress: Nearly 4M lung cancer deaths were prevented in the US from 1970–2022 thanks to effective tobacco control policies. Read the American Cancer Society study: acsjournals.onlinelibrary.wiley.com/doi/full/10.33… OncoAlert Ahmedin Jemal Farhad Islami, MD PhD Nigar Nargis

Staging laparoscopy for gastric cancer: European consensus ⁦BJS⁩ academic.oup.com/bjs/article/11…

Perioperative therapy for resectable and borderline resectable pancreatic adenocarcinoma: an Academic Gastrointestinal Cancer Consortium Study ⁦The Oncologist⁩ academic.oup.com/oncolo/article…

Oxaliplatin Dosing and Toxicity: A Cautionary Perspective on Efficacy. Read the full article: brnw.ch/21wXods #ColorectalCancer #crcsm

#ESMO25 lived up the hype for #GUOncology! 🎙️4 Presidential presentations 📜6 NEJM/AnnOnc publications Join Toni Choueiri, MD Bradley McGregor Atish Choudhury, MD PhD Bicky for highlights! Prostate: tinyurl.com/5h3frn5h Bladder: tinyurl.com/mw38yhjw Kidney: tinyurl.com/4avjatdp

Cancer of Unknown primary thankfully is not very common but this still ends up being very challenging! IHC patterns that can help guide us the origin (slide by Thor Halfdanarson and Harry Fuentes MD MSc) during CUP discussion! #OncTwitter #MedTwitter OncoAlert OncUpdates

Pathological response guides adjuvant 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy in surgically resected gastro-oesophageal cancer (SPACE-FLOT): international cohort study ➡️doi.org/10.1093/bjs/zn… 🎯 Investigates whether pathological response to

Watch-and-wait approach in high-risk locally advanced rectal cancer: outcomes after complete response to total neoadjuvant therapy ➡️doi.org/10.1093/bjsope… This study supports the safety of a watch-and-wait approach in patients with high-risk rectal cancer with a complete

In a nonrandomized phase 2 trial of adults with advanced dMMR/MSI-H noncolorectal cancers, combined nivolumab/ipilimumab showed an objective response rate of 63% and 6-month progression-free survival rate of 71%. ja.ma/4i68zWQ