Excited about ultrarapid drug discovery platforms? Check out our J. Am. Chem. Soc. Perspective pubs.acs.org/doi/10.1021/ja… on Advances in Ultrahigh Throughput Hit Discovery with Tandem Mass Spectrometry Encoded Libraries by Edith v.d. Nol and @mm_a_t_a Universiteit Leiden LED3 hub (inactive account) Leiden Science

Chemical technology principles for selective bioconjugation of proteins and antibodies - now published in Chemical Society Reviews pubs.rsc.org/en/content/art… Dept of Chemistry, IISER Bhopal IISER Bhopal SERB DSTIndia

Empowering Site-Specific Bioconjugations In Vitro and In Vivo: Advances in Sortase Engineering and Sortase-Mediated Ligation (Ulrich Schwaneberg and co-workers) RWTH Aachen #openaccess thanks to #ProjektDEAL #AngewandteReview onlinelibrary.wiley.com/doi/10.1002/an…

Check out "Chemical technology principles for selective bioconjugation of proteins and antibodies" by Vishal Rai, Preeti Chauhan, Ragendu Vimalkumar, Mohan Kumar, RAJIB MOLLA, Surya Dev Mishra and Sneha Basa From our Pioneering Investigators collection rsc.li/4aDQFXc

Analysis of N‐ and O‐linked site‐specific glycosylation by ion mobility mass spectrometry: State of the art and future directions …iencejournals.onlinelibrary.wiley.com/doi/10.1002/pm… --- #proteomics #prot-paper

Excited to share the final version in Nature Chemical Biology. Lots more mechanistic insights & characterization, including our inhibitors disrupt PPIs with mTOR components & induce lysosomal degradation of SLC15A4, & more. A promising target for autoimmune conditions. nature.com/articles/s4158…

Covalent Hits and Where to Find Them dlvr.it/T20vtn

So thrilled to share my co-first-author paper in J. Am. Chem. Soc. where we introduce the notion of amplifying chemical shift sensitivity of fluorine #NMR protein tags by linking the #19F reporter to a dynamic tautomeric species! Magnetic Resonance News #nmrchat #19FNMR #PrOFNMR pubs.acs.org/doi/full/10.10…

Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2 dlvr.it/T2PQ3f

Nice review on covalent warheads: pubs.acs.org/doi/10.1021/ac…

Check out our most recent work developing new strategies that leverage massive mRNA-displayed macrocyclic peptide libraries for covalent ligand discovery! Congrats Tong Lan and thanks for Matthew Bogyo and Scott Snyder for collaboration! pubs.acs.org/doi/10.1021/ja…

Thrilled to present our work on #Multi-equilibria platform to modify carboxylic acid in proteins at #EMBOChemBio conference. Join me Poster-no 122 to learn more about the new bioconjugation platform IISER Bhopal SERB Vishal Rai

Membrane curvature promotes ER-PM contacts in cardiomyocytes. Excited to share our work published in Nature Cell Biology today. Congratulations to Yang and the team! nature.com/articles/s4155…

Thrilled to share that, together with my colleagues Centre for Targeted Protein Degradation and collaborators Boehringer Ingelheim, we report Science Magazine the breakthrough discovery and characterization of a small-molecule that degrades most oncogenic mutant forms of KRAS. 1/8 science.org/doi/10.1126/sc…

Happy that this is finally online! Genetic code expansion approaches to decipher the ubiquitin code Chemical Reviews Many congratulations to Vera, Max and Marco! Vera Wanka Max Fottner Marko Cigler 🥂🎉🥳 pubs.acs.org/doi/10.1021/ac…

the first project of my PhD is now out J. Am. Chem. Soc. ! super proud to introduce ABAP (my first acronym!) and share our findings on how lysine acetylation modulates protein function & interactions. so surreal to see this in print pubs.acs.org/doi/10.1021/ja…

Nice investigation with modified Insulin. Congratulations to the whole team.

Biopharma and biotech companies looking for homogeneous protein and antibody conjugates? A new access channel for our technologies: app.scientist.com/domain_switche…

Thank you Vishal Rai for your mentorship and supportive through out my journey 🙂 A challenging jouney came to conclusion and I successfully defended my Ph.D. thesis.