🫘🦀Spectrum of renal involvement in Monoclonal gammopathy of renal significance (MGRS) KIReports kireportscommunity.org/post/monoclona… 👏 Nice review Tiffany Caza Sai Achi, MD Corina Teodosiu 🕊️ 🇺🇦

Update diagnostic criteria for Cryoglobulin GN type 1&2, no longer need the presence of serum cryoglobulin. American Society of Onconephrology

DD of IF-linear IgG deposition along GBM +/- TBM

🔥IgA Nephropathy has 2 faces: 🩸Inflammation→ proteinuria, hematuria, crescents, rapid eGFR fall 🧱Fibrosis → slow decline, TIF/TA, minimal hematuria 🎯Tx: steroids, budesonide, iptacopan➝ SGLT2i, RAASi, DEARA 🔗doi.org/10.1093/ndt/gf… 🆕NDT #IgAN #CKD #Nephrology

Just out in the New England Journal of Medicine! Our comprehensive Review on MGUS: Monoclonal Gammopathy of Undetermined Significance NEJM nejm.org/doi/full/10.10… 5% of people over age 50 have MGUS. Every physician needs to know and understand MGUS. Lots of Tables and

Now online in NDT Anti-nephrin antibodies in patients with IgAN and nephrotic syndrome 🧐The majority of MCD-IgAN patients were positive for circulating anti-nephrin antibodies! ▶️academic.oup.com/ndt/article-ab…

Bx for new onset NS in an older adult. Serologic work up including SPEP/UPEP IFE negative. Bx shows membranous pattern with few double contours. IgG3-k restriction and mottle EM deposits c/w PGNMID with membranous predominant pattern. PLA2R- #renalpath #pathtwitter #nephrology

A startling biopsy. Severe acute TMA in a pt with suspected scleroderma renal crisis. Massive vascular thrombosis, mucoid intimal edema, and early onion skin change associated with severe cortical necrosis. #renalpath #nephrology #pathtwitter

Join GlomCon this Sunday Pathology on Monoclonal Gammopathy Related Renal Diseases by Dr. Suxia Wang ID: 817 4374 4653 Passcode 202122 sign up 👉 bit.ly/signup-glomcon #GlomCon

Distinguished renal pathologist Dr. Michael Kashgarian died peacefully at home in Hamden, CT on June 28, 2025 at the age of 91.  A founding member of the Renal Pathology Club (which would become the RPS), he was a past President of the RPS, (1/2)

APOL1-associated nephropathies: From Dr. Kelly Smith at GlomCon

Unusual cause of collapsing glomerulopathy - light chain crystalline podocytopathy. From Dr. Kelly Smith at GlomCon

26/n #ECNeph Dinesha Sudusinghe manjusha yadla Int Society of Nephrology Sandhya Suresh HPE of monoclonal ITG

What is your diagnosis in a 35 y/o male with paraplegia and chronic osteomyelitis who presents with nephrotic syndrome? Bonus: What subtype would you suspect based on the clinical history? #DiagnoseThis #nephx #pathx #renal #kidneypath

Cryofibrinogen-associated nephropathy shows MPGN pattern with no Igs and complement staining. Unique tubular structure with central bores and multiple layers, larger than those in immunotactoid GN by EM kireports.org/article/S2468-…

This biopsy shows the characteristic features of uric acid nephropathy (commonly known as gout), which results from precipitation of uric acid in the kidney parenchyma. Tophi frequently occur in the medulla, and usually consist of central regions of acellular, granular material

#MassSpectrometry of Minimal Change Disease and Focal Segmental Glomerulosclerosis #MCD #FSGS #VisualAbstract by Sophia Ambruso kireports.org/article/S2468-…

Linear staining in GBM, Bowman capsule, TBM in pt with heavy chain deposition disease. Granular/smudgy staining noted in mesangium

Unusual granular casts with annular appearance. Light chain, hemoglobin, myoglobin, chromogranin casts excluded. Patient on IV vancomycin. Suspicious for vancomycin cast nephropathy. pubmed.ncbi.nlm.nih.gov/31871855/ #renalpath #pathtwitter #nephrology

#IgA-Dominant Mesangial #Proliferative #Glomerulonephritis in Prolidase Deficiency doi.org/10.1016/j.ekir… #KIRNephrologyRounds