Tested out an awesome new ER probe in an immature cardiac myocyte #microscopy #iSIM #fluorescence

A date for your diaries: 23-26 September 2024. Biochemical Society is running a membrane contact site conference (2.5 days) in Edinburgh. eventsforce.net/biochemsoc/180… High profile speakers & full programme announced soon. Low price registration, with grants & bursaries.

The 6th Annual Mitochondria Symposium UCLA will take place on Dec 7th-9th. Full 3 days, including unconventional Mito activities. With 30 invited speakers and panelists. Registration & abstract submission: uclamitosymposium.com

We have new original research fro Wei-Ke Ji and Juan Xiong (Wuhan) demonstrating that lipid droplets (LDs) contact the Golgi, and that these contacts contain VPS13B, which promotes their formation in cells fed with oleic acid to enlarge LDs. journals.sagepub.com/doi/10.1177/25…

Every PI’s job when they see their postdoc agree to join MDPI special issue editorial

For tips and trick for optimising your ER fixation, we’ve summarised the conversation following @guijacquemet's request for advice. Featuring Andy Moore Chakrabarti Lab @DamstraHugo and Christoph Spahn! focalplane.biologists.com/2023/11/02/com…

Local glycolysis fuels actomyosin contraction during axonal retraction, say Renata Santos, Diana Zala and colleagues Inserm Paris 5 Ipnp @univ_paris: bit.ly/3Sfdael #CellMetabolism #Cytoskeleton #Development #neuroscience

After a VERY long journey we are happy to share our characterization of the MAPL KO mouse. See how MAPL loss leads to lean phenotypes, dysregulated bile acid metabolism, wild changes in the gut, ultimately leading to hepatocellular carcinoma. doi.org/10.15252/embr.…

Our manuscript "High-Throughput Identification of Calcium Regulated Proteins Across Diverse Proteomes" biorxiv.org/content/10.110… is on BioRxiv! This has been a fun collaboration with the Schweppe Lab Devin Schweppe UW Genome Sciences Rose Fields and our lab @uwpharmacology. Tweetorial below

📣 Save the Date - 16-20 September 2024 #mito #mitochondria

Other #mitophagy updates this week! Finally mechanistic insights this time.. biomed.news/bims-tofagi/20… biomed.news/bims-tofagi/20… highlights: -The ER membrane protein complex restricts mitophagy by controlling BNIP3 turnover -OPTN provides a mitophagy contact site for TBK1

First preprint from my laboratory, commendable efforts from Tak Shun Fung and Amrapali Ghosh and a superb collab with Marco Tigano and Higgs Lab biorxiv.org/content/10.110…

Proud moment when your mentor Higgs Lab visits your lab… Three generations in one 🖼️

Scientists discover ‘division of labor’ in mitochondria | Science | AAAS science.org/content/articl…

Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via HSP27 ft. liz gallagher, Peace Oloko, tessa, Erika Holzbaur-Howland (UPenn Physiology), Elizabeth Brown & @spruce_lynn (CHOP Research) cell.com/current-biolog…?

science.org/doi/10.1126/sc…

New review by the Thompson lab Memorial Sloan Kettering Cancer Center. embopress.org/doi/full/10.10…

Wow very big news for biomedical research

The secret life of LIRs: Binding to Atg8-family proteins is just a fraction of what LIRs can do....