Hurray! 🎉 After years of perseverance, my PhD is officially complete. It’s been a rollercoaster of challenges, growth, and breakthroughs. While this chapter closes, my curiosity and passion for discovery only grow stronger. #AGLAB IISER Bhopal Dept of Chemistry, IISER Bhopal #Phddone #farewell

Engineering Reaction Pathway of Non-heme Fe Oxygenase Using Ancestral Sequence Reconstruction | Journal of the American Chemical Society Alison Narayan University of Michigan Narayan Lab @ UMich Michigan Research #Engineering #Reaction #NonHeme #Fe #Oxygenase #Ancestral #Sequence pubs.acs.org/doi/10.1021/ja…

With profound sadness, we announce the passing of Sir Fraser Stoddart, Nobel Laureate and cherished member of Northwestern. His groundbreaking contributions transformed the field of #chemistry and inspired countless scientists worldwide. ➡️ bit.ly/stoddart-in-me…

A new paper reports a strategy to induce liquid-liquid phase separation in E. coli to enhance the performance of artificial metalloenzymes nature.com/articles/s4158…

I'm excited to start the year with CellChemicalBiology paper about the machinery that assembles #Geobacter #cytchrome OmcS #nanowires! Led by the super-talented Cong Shen Aldo Salazar-Morales Gu Yangqi Sibel Ebru Yalcin with Kallol Gupta. Yale MB&B Yale West Campus 1/7 dlvr.it/THNSHK

When you’re a grad student (at least back in the day), the conventional wisdom was to change your research direction or organism as a postdoc — to ensure you got some educational value out of the next stage. One of the main reasons I chose the postdoc lab I did was because when

Using our biocompatible chemistry, we can assemble branched and macrocyclic peptides directly on folded proteins. Congrats to Sven Ullrich, Santhanalaxmi Kumaresan, Marina Rahman, BishvanweshaPanda and Richard Morewood on their paper just published in Chemical Communications! doi.org/10.1039/D4CC06…

Investigating the Correlation between Product Release and Solvation in Cytochrome P450 Enzymes | ACS Catalysis pubs.acs.org/doi/10.1021/ac…

Announcing Evo 2: The largest publicly available, AI model for biology to date, capable of understanding and designing genetic code across all three domains of life. arcinstitute.org/manuscripts/Ev…

A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb. go.nature.com/4i9BpEx

In a new Science study, researchers present ESM3, a protein language model that enables the programmed generation of protein structure and sequence in response to user prompts. Learn more: scim.ag/4jhJ9Wa

This isn't science fiction. This is real sequencing biotechnology just introduced by Roche. Wild and wonderful.

The long-term goal is to grow human organs that can be harvested for transplantation go.nature.com/4l6YzNd

Today in Cell we report the use of prime editing to correct several mutations that cause alternating hemiplegia of childhood (AHC), a rare and devastating neurodevelopmental disorder, in patient-derived cells and in two mouse models. drive.google.com/file/d/1ibC50t… 1/10

Something a little different from our group. We designed a regeneration system for ATP(gamma)S, a reagent that normally costs ~$30,000/g. This allows for more practical enzymatic thiophosphorylation to make a number of interesting/funky thiophosphates. chemrxiv.org/engage/chemrxi…

A copper enzyme for Lewis acid biocatalysis bit.ly/450Kmei

Unlocking potential: the role of the electron transport chain in immunometabolism: Trends in Immunology cell.com/trends/immunol…

Scientists have created a tool that manufactures working proteins directly on the surfaces of cells go.nature.com/4meNl9U

Nature research paper: Diffusing protein binders to intrinsically disordered proteins go.nature.com/4lTr0Pl