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The genetic architecture of protein interaction affinity and specificity nature.com/articles/s4146… by Guillaume Diss @AlexBendel_ + Andre Faure @ajfaure.bsky.social

New synthetic biology / gene regulation lab opening in Zurich! We’re studying how to control cell state transitions – for example, making diseased cells healthy or creating new cellular functions – using systematic perturbations, single-cell genomics and machine learning. 🧵1/4

Evolutionary genetics folks, does anyone know of a data practical suitable for undergrad teaching that focuses on sex ratio theory or sex chromosome meiotic drive? Before I invest a lot of time developing one I thought I ask around first! Thanks

In a Perspective just published in Development I set the stage of our knowledge at the time, describe the screen itself and then describe how it revolutionized developmental biology 3/n journals.biologists.com/dev/article/15…

Ægteskab og skilsmisse som kulturhistorisk kampplads. Glæd dig til at læse, se og lytte til #MånedensForsker med historiker @karenvallgarda #dkforsk Københavns Uni #dkhistorie

Beyond thrilled to present our O-MAP—now *published* Nature Methods (!!!) O-MAP is a powerful new method for biochemically "dissecting" the subcellular microenvironment around an RNA of interest, using off-the-shelf parts and standard manipulations. 🧵 nature.com/articles/s4159…

Det her svarer fuldstændigt til mine erfaringer. Mange af mine studerende har allerede jobs inden de afleverer specialet - og det er i næsten alle tilfælde på grund af deres studiejobs. Når man presser det, gør man også overgangen til arbejdsmarkedet sværere

Exciting discovery by Dr Rippei Hayashi from #JCSMR and A/Prof Peter Andersen at Aarhus University They’ve uncovered tPAF, a testis-specific regulator essential for sperm formation in Drosophila. Major step forward in understanding #Spermatogenesis! #ourANU #AarhusUni jcsmr.anu.edu.au/news-events/ne…

Excited to share our unexpected finding: piRNA pathway designed to protect the genome from invading nucleic acids created a population of selfish small RNAs that have perpetuated themselves for the past hundred million years of mammalian evolution. biorxiv.org/content/10.110…

AlphaFold can predict protein, DNA, or RNA complexes.. BUT is it easy to determine the reliable interactions?🤔 ➡️ AlphaBridge will identify the most confident interactions, making your analysis easier! 🌐Try it here: alpha-bridge.eu 👀Read more: biorxiv.org/content/10.110…

A reminder that our new lab at Molekylærbiologi - Molecular Biology has a fully funded postdoc position available. Our group integrates biochemistry, cryoEM, and single-molecule imaging to explore the mechanisms of DNA repair complexes. 🧬🔬 sites.google.com/view/alconlab/… Please share with your colleagues!

I can now be found at uwe-ohler.bsky.social . Will likely also link to Mastodon and let you know. #eXit

i can guarantee that no bluesky team members will be sitting with a presidential candidate tonight and giving them direct access to control what you see online

Following the ongoing (primary USitizens) Elon-inspired exodus here, giving bsky another shot - Igor Ulitsky 💔.bsky.social

Jeg har skrevet lidt i Altinget om vigtigheden af at investere i forskning, og om hvorfor jeg mener, at vi i dag ikke fordeler pengene optimalt. Vi kunne få langt mere ud af det, hvis vi gentænkte ideen med forskningsreserven. #dkpol #forskpol altinget.dk/forskning/arti…

If you have ever wondered whether the PAML documentation could be more interactive... We have good news for you! The PAML GitHub repository has been updated and a fresh PAML Wiki is now available for you to navigate the PAML documentation! 📄💻 (1/n) github.com/abacus-gene/pa…

Last reminder: Postdoc position focused on RNA degradation biology, CRISPR gene editing and Nanopore long read sequencing in my laboratory in Copenhagen: please spread to great candidates. Deadline 15 Jan. candidate.hr-manager.net/ApplicationIni…

Super proud - our new work about two troublesome TEs spreading into several Droso species in just a few decades; it was so much fun to work with the amazing Riccardo Pianezza Almorò Dr. Sarah Signor rdcu.be/d5G1M

Crack the code: Have you ever wondered whether the “histone code” is only present on histones? Is it exciting that a similar “code” embedded in non-histone proteins is also involved in gene regulation? Check out our new preprint on a “histone mimic code”: biorxiv.org/content/10.110…

I am super proud to share the first Andergassen Lab preprint! Here, we introduce a new framework to decode the non-coding genome, led by the outstanding work of Tim Hasenbein and co-authors Sarah Hoelzl, Stefan Engelhardt TU München DFG public | @[email protected] Non-coding RNA in the cardiovascular system 👇🧵