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Now Online MYC between transcription and replication dlvr.it/Sdgy7g

Another day, another #NRMCBResearchHighlight! 🥳 We highlight work by Elmar Wolf' and Martin Eilers's labs Universität Würzburg #UniWürzburg, recently published nature: go.nature.com/3uIsfb7

New therapies for a certain type of #pancreatic #cancer: Elmar Wolf Universität Würzburg #UniWürzburg is working on this. He has now received a €2 million ERC Consolidator Grant from the EU. Congratulations! #ERCCoG Wolf Lab for Tumor Biochemistry European Research Council (ERC) go.uniwue.de/wolf-erc

Integrator is a global promoter-proximal termination complex dlvr.it/Shtx7G

So excited to share that my thesis work is out now at Molecular Cell! Karen AdelmanLab and I show that U1 snRNP increases RNA Pol II elongation rate within AT-rich introns, thereby reducing the likelihood of Pol II termination or arrest. Highlights below! authors.elsevier.com/c/1gobY3vVUPNx…

Great to see the conclusions from a recent paper from our lab (Stein et al 10.1016/j.molcel.2022.10.004) so nicely recapitulated in a different system !!!

My RNA didn’t degrade, it just underwent a rapid unscheduled disassembly into nucleotides !!

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Happy to announce the final version of our paper is now available Nature Communications! nature.com/articles/s4146… Thank you to co-authors Kavya, Geoff Nelson Dr. Helena Zomer, Debarun, Irene, Reza, Huanyu, AdelmanLab and Prabu for a great collaboration of transcription and development expertise!

All the points in a single blog: backscattering.blog/2024/03/31/som…

Looking for an exciting #PhD project in #molecularBiology? How about this question: what determines a gene's end? Most human genes have alternative ends, the choice of which is important for health and disease. Yet we still don't understand how this choice is made!

Very proud to have been awarded an ERC Consolidator grant for research on neuronal RNAs! Rock on, team!

Delighted to share our #NightScience tale: "A tetramer of BCL11A is required for stable protein production & fetal hemoglobin silencing," in Science Magazine. Co-led by Zheng Ge, Yin Maolu, & me, here’s a tweetorial about our puzzle-solving adventure! 1/7 tinyurl.com/2tpaaua3

Join organizers AdelmanLab, Kristian Helin to discuss emerging research Keystone Symposia #Epigenetics in #Development and Disease #KSEpigenetics25 keysym.us/KSEpigenetics25

Very excited to share that my thesis work is out in Molecular Cell! We trained a Structure and Omics informed Classifier (SPOC) to score binary AlphaFold multimer (AF-M) predictions by structural quality and consistency with experimental omics datasets. cell.com/molecular-cell…

Excited to be at Keystone Symposia for first time ! Looking forward to plenty of science&fun at #Epigenetics in #Development and Disease #KSEpigenetics25 keysym.us/KSEpigenetics25 #RNA #GeneReg #GeneRegulation