Chao Liu
@ploy_a_im
Ph.D., Institute of Microbiology, Chinese Academy of Sciences;
CRISPR-Cas system, TA system, phage and microbes.
ID: 1612053658694455296
08-01-2023 11:48:56
40 Tweet
33 Followers
148 Following
Joshua Modell lab and I are excited to celebrate #WorldPhageWeek this year with our new preprint, showing how CRISPR-Cas9 systems can respond to phage-encoded anti-CRISPRs and ultimately counterbalance Acr-phage infections! biorxiv.org/content/10.110…
Just missing April fool's, here is something that is no laughing matter: nature.com/articles/s4156… In Nature Microbiology, we describe how a prophage avoids autoimmunity from its own defence systems
Phage vs. Bacteria: New findings! Phages use their own tRNAs to evade bacterial defenses like retrons and PrrC. Huge thanks to Azam for his hard work! in Nature Communications nature.com/articles/s4146…
We cracked the tRNA specificity of FaRel2 toxSAS. A fun collaboration with the Suzuki Lab., Garcia-Pino Gemma C Atkinson and Polikanov. Out in Science Advances! science.org/doi/10.1126/sc…
Our study on how diet may regulate the gut phageome-bacteriome interaction relaying to a disease protection, #IBD, is freshly out at Gut Journal gut.bmj.com/content/early/…
The sequel to our DRT2 story is here, and this one is once again full of surprises! This time around, the Sternberg Lab teamed up with the Wiedenheft Lab to study how DRT9 reverse transcriptases provide antiviral immunity. Here’s what we found: biorxiv.org/content/10.110…
Excited to share our last collab paper, now out in print Science Magazine!🎉 We reveal how dITP synthesis activates a SIR2 NADase effector to block phage infection! 🛡️🧬 science.org/doi/10.1126/sc…
Exciting news! Our latest paper is out in Nat. Microbiol. Nature Microbiology We show that a sub-lineage of 7th pandemic V. cholerae has acquired mobile genetic elements packed with phage defense systems—rendering it multi-phage resistant 😳 ..... 1/3 nature.com/articles/s4156…
