Our recent study out today in PLOS Pathogens identified cell type specific immune responses to Candida auris skin infection using single cell transcriptomics. Thank you Mihalis Lionakis, Mihai Netea and Vinod for collaborating in this study ! journals.plos.org/plospathogens/…

Fantastic EVOLVEpro!

L1TD1 activates L1 ORF1p via binding. biofactoid.org/document/6387a…

New review out today in Nature Biotech on nanopore-based protein sequencing. Feels... like... something... coming... soon... 👀

A small story I found when I was a kid in fungal pathogen field. Rapid in vitro evolution of flucytosine resistance in #Candida #auris pubmed.ncbi.nlm.nih.gov/40099908/

Deadly fungi are becoming drug-resistant. A new compound could beat them | Science | AAAS science.org/content/articl…

My collaborative work with a TissueHome member on L1TD1 is now online in eLife - the journal elifesciences.org/articles/96850

A short letter in which we demonstrated that phosphatidylinositol transfer protein Pdr16 is responsible for azole resistance in Candida auris. The upregulation of these proteins may also be involved in resistance to amphotericin B and flucytosine. journals.asm.org/doi/10.1128/sp…

Wang lab shows that in response to echinocandins C. albicans thickens its wall while C.auris stiffens the wall via upregulating B1,6 glucan and strengthening B1,6 - Mannan interactions. nature.com/articles/s4146… ECMM YoungECMM ISHAM The Young ISHAM MRC Centre for Medical Mycology

Fifty shades of Brown is online now! #Candida #auris