Super excited for this to be out! We hope CellWalker will help people get more out of their scATAC-seq data. It should be especially useful for samples with low coverage and rare cell types.

Our work “A transcriptional switch governs fibroblast activation in heart disease” previously on bioRxiv is now online nature. A great team effort Gladstone Institutes Deepak Srivastava and all the fantastic collaborators. A new thread /1 👇 nature.com/articles/s4158…

So excited for this paper to be out! Amazing to work with Michael Alexanian. He managed to bring together an incredible team of scientists to generate a vast amount of data to answer a fundamental question. Looking forward to more collaborations in the future! nature.com/articles/s4158…

Thrilled to share that my grad work from Nowakowski_Lab characterizing the epigenomic landscape of the developing human cortex is out today in nature as a part of the #BICCN collection. Honored to have it published along with this monumental body of work! nature.com/articles/s4158…

Very useful method for interpreting single cell ATAC-seq datasets, great work from Pawel F. Przytycki

We are proud to call @BroadInstitute fellow Brian Cleary an BU Computing & Data Sciences (CDS) assistant prof + BU Bioinformatics Biological Design Center, Boston University Kilachand Center, Boston University Boston University Biomedical Engineering BU Biology. Read what Boston University profs @TomTullius, Chris Chen, @AnaFiszbein, and Azer Bestavros said about it at bu.edu/cds-faculty/20…

Last chapter published yesterday in ERL IOPscience! doi.org/10.1088/1748-9…. We modeled climate change impacts to peat swamps in SE Asia by applying deep learning to🛰️soil moisture. Drier climate portends drier soils and higher fire risk 🫥

Cell Layers! @apblair95's really cool tool for scRNAseq cluster determination with multi-resolutions parameters. Featuring Pawel F. Przytycki and colleagues. academic.oup.com/bioinformatics…

Huge congrats to Michael Alexanian! Keep an eye out for his lab, it's going to do amazing things!

Amazing opportunity to work in a dynamic environment full of young faculty!

New Year New bioRxiv 🥂 Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis - this was a great team effort with fantastic collaborators. A thread 🧵/1 biorxiv.org/content/10.110…

Thank you to American Cancer Society and the BU-BMC Cancer Center for funding early stage investigators!

The question of what makes us human remains enigmatic, but we investigate how enhancer hijacking, or fondly, "HARjacking", may have played a role in human-specific genome evolution in our study now out in Science Magazine ! science.org/doi/10.1126/sc…

First lab picture! Less than a year in a growing quickly. Thank you BU Computing & Data Sciences (CDS) for the great working environment (and the great views!)

An accompanying News & Views by Pawel F. Przytycki is also available! nature.com/articles/s4358… 👉rdcu.be/dhIZ0

Finally (a year later) I had a chance wrap up this project I started as a postdoc. We show that using a cell type tree with single cell chromatin accessibility data allows us to identify a very interesting set of eQTLs that regulate genes in context and cell-type specific ways.

Join the #ResearchOnTap conversation about Health Data Science. Hear from BU Experts on how #DataScience can shape #Healthcare practices, policies and our understanding of the world. Host: Debbie Cheng, Boston University School of Public Health Population Health Data Science Program ➡️ spr.ly/6013u0Sn1

And now out in genome biology! genomebiology.biomedcentral.com/articles/10.11… . Additionally, if you're generally interested in using cell type hierarchies with your single-cell data, check out our in-progress work CellWalker2 which includes those and much more: biorxiv.org/content/10.110…