So happy to see this out today - our ultra-fast genome browser GW v1.0 #Genomics 🚀 biorxiv.org/content/10.110…

End-to-end simulation of nanopore sequencing signals with feed-forward transformers biorxiv.org/cgi/content/sh… #biorxiv_bioinfo

VERY excited to share SeqTagger with the world! If you want to learn more about our super-fast and accurate demultiplexing tool for direct RNA-sequencing (DRS), check out the thread below. bit.ly/3ClVYxG (1/15) 🧵

Very excited to announce our preprint on adapting the Oxford Nanopore Cas9 workflow for R10 flow cells. This is work from the amazing Veronika Scholz and Veronika Schoenrock and team MGZ - Medizinisch Genetisches Zentrum, and is also my very first senior author paper 🧵biorxiv.org/content/10.110…

Interested in multiplexing samples for nanopore dRNA sequencing with the new chemistry? Check out our newly released RNA4 model! 4 barcode model available here: github.com/KleistLab/Warp…

2/6 📊 Performance highlights for RNA004: - Calibrated performance for difference target accuracy modes (95-99.9%) at high yields - Extremely low cross-talk between barcodes - 10 fold runtime improvement compared to RNA002

5/6 ⚡️ Processing speed benchmark: WDX4: 2.2 min/100k reads (on 8 CPU cores, decreases linearly with number of cores)

Congratulations to PoL postdoc Lukáš Pekárek @LukasPekarek1 from the Jahnel group Marcus Jahnel 💛💙 for being awarded the prestigious Peter and Traudl Engelhorn Scholarship! Lukáš researches long RNA structure and their changes during phase separation. Read more: physics-of-life.tu-dresden.de/news/2024/11/1…

🧬Excited to share our new preprint! DMS chemical mapping, a key technique for studying RNA structure. It is assumed that low DMS reactivity=WC, high=non-WC. However, analyzing 7,500 RNA structures containing known 3D structures reveals it's not simple. doi.org/10.1101/2024.1…

Check out the results of the most recent round of the RNA Puzzles endeavor for RNA 3D structure prediction! nature.com/articles/s4159…

Interested in joining our growing interdisciplinary team studying viruses, RNA, and condensates? Looking for a postdoctoral position? Please consider joining us in Cambridge, UK, or drop us a line to discuss these opportunities: jobs.cam.ac.uk/job/49901/

How can sequencing reveal how viruses spread through hospitals? 🦠 Join CHOP’s Dr. Robert Potter as he shares how he uses Plasmidsaurus long-read sequencing to investigate norovirus transmission within hospitals. 🗓️ Sept 5th, 10am PT 👉 Register: hubs.ly/Q03FnL-L0

We’re working hard to accelerate your research! You can now view the predicted amino acid sequence of each coding region and per-base quality scores directly on your results page, giving you clearer insight into your sequence results at every position.

🌎👩‍🔬 For 15+ years biology has accumulated petabytes (million gigabytes) of🧬DNA sequencing data🧬 from the far reaches of our planet.🦠🍄🌵 Logan now democratizes efficient access to the world’s most comprehensive genetics dataset. Free and open. doi.org/10.1101/2024.0…

Hey dinos 🦖 we’ve been cooking up something new in your library… Now you can: 1. Quickly align any two sequences from your history or uploads 2. Search across everything you've sequenced with us We'd love a few of you to try early access & help build this. Reply if you're in!

So cool to see this being built by our incredible engineers! And there's so much more ...