Always exciting and rewarding to share what we do in the lab with the new generations. Hopefully we even managed to inspire some young brains! So happy to be able to participate in #Unistemday2024 🧠🧬🔬Lund Stem Cell Center UniStem Day 2024

Please help us spread the word: We are looking for 2 group leaders IMBA, a basic research institute at the Vienna BioCenter. I started a lab at IMBA 14 years ago and it has been an incredibly rewarding experience. The dynamic and collaborative research community ...

Looking forward to the exciting program International congress on transposable elements 🧬🤩!!

Vivien Horvath shows very nicely SVA elements form mini-heterochromatin islands in neuronal precursor cells, mediated by ZNF91, protect against cis-regularly effects on nearby genes #ICTE2024

Very nice talk by Vivien Horvath at #ICTE2024 about the cis-regulatory impact of SVAs on human brain health and disease 👏. Check out the preprint 👇 Johan Jakobsson Lund Stem Cell Center biorxiv.org/content/10.110…

Sophie Lanciano (Gael Cristofari lab) uses clever cas9-guided ONT targeted sequencing to uncover principles underlying differential methylation of young L1 loci and effects on their local genomic environment. Great work and great talk! #ICTE2024 cell.com/cell-genomics/…

We are recruiting! We are looking for new members (postdocs and/or bioinformaticians) to join our team. Translational projects on neuroinflammation, transposable elements and single cell analysis. Email or DM me for more info! Lund Stem Cell Center Please RT! molecular-neurogenetics.lu.se

Happy to share our review on viral genomics, where we discuss different methods to sequence viral genomes in a range of research and applied environments. Viral genome sequencing methods: benefits and pitfalls of current approaches portlandpress.com/biochemsoctran…

Pleased our study led by Gabriela O. Bodea of L1 activity in mouse parvalbumin (PV) interneurons has now been published Nature Neuroscience nature.com/articles/s4159… Props also to Juan Manuel Botto eugeniaferreiro Francisco J S-L Anthony Hannan + all the authors A brief recap 🧵👇 1/n

The impact of LINE-1 retrotransposons on neurobiology is not fully understood. Our new research in Nature Neuroscience sheds light on LINE-1 activity in PV interneurons, sparking fresh perspectives on its role in neurobiology. #neuronaldiversity #neurogenetics nature.com/articles/s4159…

On my way to #eshg24 in Berlin. See you there! Two oral presentations from the lab:

If you are at #eshg24 and would like to know how a transposable element and its epigenetic regulators cause a neurodegenerative disorder come to my talk on Monday at 11:00 in room A2!🧬🧠Johan Jakobsson Lund Stem Cell Center

Are you at #eshg2024 and want to know more about TRIM28, transposable elements and neurodevelopmental disorders? Come to my talk today at 18:45h in the “Novel genes in neurogenetic disorders” session 🧠🧬 Johan Jakobsson

Our study on XDP, SVAs, ZNF-91 and heterochromatin has now been published in NatureStructMolBiol. "Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease" nature.com/articles/s4159… 1/n

I am thrilled to see my first postdoc paper published in NatureStructMolBiol! 🌟🧠🧬 “Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease” nature.com/articles/s4159… 1/n 🧵

Proud to have contributed to this fantastic study led by Christopher Douse . HUSH for the world! nature.com/articles/s4146…

We started the academic year by discussing transposons for two days at the beach! Lots of new data soon coming your way… Lund Stem Cell Center #TEs #transposons

Delighted that this is finally out! Thanks to Geoff Faulkner Todd Macfarlan and the other reviewer for good and constructive comments that arrived in my inbox the day after my second child was born... paper here nature.com/articles/s4146…. Short reflection on new stuff...

Our superstar postdoc Raquel Garza (together with co-author Diahann Atacho) won the runner-up award for best paper of the year Lund Stem Cell Center ! Science Advances science.org/doi/10.1126/sc…