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EVENT: Registration is now open for our next MCRC Seminar featuring Associate Professor Alastair Lamb from Oxford Cancer. "Unravelling clonal dynamics in localised prostate cancer in the spatial ‘omics era" 📅 Thursday 3rd October 2024 ⏰ 10am-11am 🔗 eventbrite.co.uk/e/102484845832…

Three big questions in prostate cancer presented by Prof. Alastair Lamb at the #FCIsymposium2024 in Kuopio.FCI Finnish Cancer Institute UEFcancer University of Eastern Finland Leena Latonen

Fun but sad final day in Oxford which happened to coincide with some special milestones on natal & RARP fronts What an awesome team I've had the privilege of working with OUH & Nuffield Department of Surgical Sciences over past 7 years!! Now for a bit of gardening & then a new season awaits...

🚨The Weiner lab is open for business🚨 🔎Searching for a Data Scientist to lead some impactful research in #ProstateCancer genomics🧬 🙏Please the word! Cedars-Sinai Cedars-Sinai Academic Medicine @UroResidentsCS Cancer at Cedars-Sinai PCF Science Prostate Cancer Foundation CDMRP 🔗tinyurl.com/4ypennsy

Just out in The BMJ, our "Uncertainties in Practice" article on #LATP vs #TRUS We highlight evidence so far, discordance between recommendations (European Association of Urology (EAU) vs NICE vs Amer. Urol. Assn.) & need for nuance (!) Not long now until TRANSLATE Trial... bmj.com/content/387/bm…👈

Delighted to finally share our exploratory article showing utility of RNA-based phylogenetics compared to DNA approaches as benchmark journals.plos.org/plosone/articl… Originally intended as companion piece to nature.com/articles/s4158… #SPACE_Study #SpatialProstate youtu.be/YdzF0-PFXhc

•Are you a data scientist / bioinformatician / computational biologist? •Are you interested in #SpatialGenomics? •Do you want to apply your skills to big questions in #ProstateCancer? Apply here!! 👇 (closing date 12th Feb) qmul-jobs.tal.net/vx/mobile-0/ap… #SPACE_Study #Organscale

"We all love the pretty pictures we get from #SpatialTranscriptomics but the real value lies in the ability to precisely determine the cellular composition & cell-cell relationships - not possible with bulk RNA or even scRNA approaches" 💯% well said Omer Ali Bayraktar! 👏 #FoG2025

Great couple of days at #FoG2025! ■In 2024 there was one talk & 2 posters on #SpatialGenomics! (x.com/LambAlastair/s…) ●This year, 2025, there are 41 talks, a distinct stage, a discussion zone for spatial omics...oh, and a #SpaceShip - excellent!! The Festival of Genomics & Biodata 10x Genomics

TRANSLATE Trial results European Association of Urology (EAU) EAU Madrid, 10am Sunday 23/3/25, Green Area eURO Auditorium 1. #LATP v #TRUS prostate biopsy, n=1126; 1ry outcome GGG>=2 cancer detection, 2ry = infection, other complications, cost-effectiveness; Alastair Lamb Bryant_Lab Nuffield Department of Surgical Sciences OCTRU Trials Hub

Alastair Lamb received an Advanced Clinician Scientist Fellowship from our Research Careers Committee to detect lethal #prostatecancer clones, establish non-invasive biomarkers & develop a tool to identify clones from standard biopsy samples. #CRUKFunded | Alastair Lamb | Queen Mary University of London

Excited to announce #TRANSLATE_Trial outcomes will read out at 10am Sun 23rd March in eURO Auditorium 1 #EAU25, Madrid Synchronous embargoed publication in The Lancet Oncology #LATPvsTRUS - we'll finally give you the answer Hope to see you there! @GUCast Bryant_Lab Alastair Lamb

Breaking news pod - TRANSLATE trial just presented at #EAU25 with co-publication The Lancet Oncology Bryant_Lab Alastair Lamb TRANSLATE Trial. Discussant Declan Murphy Deep dive on GU Cast just released youtu.be/QdWlFy2zrHU?si…

Trial CI Bryant_Lab delighted to read out #TRANSLATE_Trial results during #GameChanger session European Association of Urology (EAU) #EAU25 Thank you to all our investigators, recruiting sites, funders National Institute for Health and Care Research and, most importantly, our 1126 pts! thelancet.com/journals/lanon… Trial visual abstract below ⬇️

Excellent talk from Sandy Figiel in European Association of Urology (EAU) #EAUlab session at #EAU25 presenting our cool data (I'm bias!) on #SpatialTranscriptomics & #ClonalAnalysis to detect unique features of metastasing clones in #ProstateCancer. Oxford Prostate Cancer Biology Group #SPACE_Study #3DLightsheet

Local anaesthetic transperineal biopsy versus transrectal prostate biopsy in prostate cancer detection (TRANSLATE) sciencedirect.com/science/articl… The TRANSLATE trial was a randomized clinical study comparing local anaesthetic ultrasound-guided transperineal biopsy (LATP) and

V grateful to Declan Murphy for his excellent, provocative & thoughtful "discussant" response to #TRANSLATE_Trial read-out by Bryant_Lab Alastair Lamb Nuffield Department of Surgical Sciences Sashi Kommu Ben Eddy 🇺🇦 Hide Yamamoto Matthew Liew Watch it again in full here ⬇️ youtu.be/O4-wKmhza6Y

The team is at #MakingProgress, connecting with the prostate cancer research community. Looking forward to exciting discussions! #ProstateCancerResearch #TeamScience Prostate Cancer UK Nuffield Department of Surgical Sciences Dimitrios Doultsinos

Co-Chief Investigator Bryant_Lab outlines #TRANSLATE_TRIAL journey during Nuffield Department of Surgical Sciences #SurgicalGrandRounds this morning. OCTRU Trials Hub SITU Oxford #SGR #Oxford_Urology

Top 20 urology journal impact factors 2025!! 👏 Was struggling to find these so jotted them down from Clarivate JCR and thought would share. Congrats to everyone!! Let's keep up with the excellent research (Discl: apols for any mistakes/typos)