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@dhyasui ASHG LaSalle Lab Dr. Janine LaSalle BMCDB.UCDavis UC Davis Research Congratulations on the talk and great work! Osman Sharifi

Osman Sharifi Great talk Osman!! Packed room 🙌🏼

The LaSalle lab is well represented at ASHG2023! ASHG UC Davis Integrative Genetics and Genomics UC Davis Neuroscience Consortium ธีระวัฒน์ ธีระวัฒน์ UC Davis Graduate Studies

Leading the world is the California way — including when it comes to research. University of California researchers were among the most cited in the world in 2023. Our world-class university system continues to be among the most influential in the globe.

These are the median days of review time, & then you pay $2K-$10K for open access. This is the direct result of the scientific community not only tolerating this, but coveting & valuing a publication in this portfolio of journals. We're all equally to blame for this to transpire.

Sex-specific single cell-level transcriptomic signatures of Rett syndrome disease progression biorxiv.org/cgi/content/sh… #biorxiv_genetic

Ecstatic to bring you our new preprint and the bulk of my thesis work investigating sex differences and examining the effects of mosaicism in Rett syndrome mouse and human cortex at the single cell level. biorxiv.org/content/10.110…

Excellent work by Chunyang (Jason) Dong creating a biosensor for opioid detection in vivo!

Congrats to my friend Osman Sharifi on completing his thesis! The team used longitudinal single-nucleus RNA sequencing with Rett syndrome mouse model, uncovered stronger transcriptional dysregulation in females, and identified key disease-related changes nature.com/articles/s4200…

Here Sharifi et al contribute to our understanding Rett syndrome through single-nuclei RNA-seq in cerebral cortex of the Mecp2e1 mutant mouse model. @lasallelab, Dr. Janine LaSalle, @dhyasui, Osman Sharifi, Ian Korf, Gerald Quon nature.com/articles/s4200…

New research by the MIND Institute's Janine LaSalle shows how Rett syndrome affects females and males differently and shows the value of studying female mouse models of Rett. LaSalle is a professor of microbiology and immunology at UC Davis Health. bit.ly/48hWNnb

Female cortical cellular mosaicism underlies shared MeCP2 and PCB impacted gene pathways biorxiv.org/content/10.110… #biorxiv_sysbio

Female cortical cellular mosaicism underlies shared MeCP2 and PCB impacted gene pathways biorxiv.org/content/10.110…