Organoids Are Us is a symposium to report and discuss the latest advances in #organoids to tackle unanswered biological and clinical questions. 📆23-26 September 2025 📍Glasgow, Scotland Only two weeks left to submit your abstract. Register now! 👇 bit.ly/4nrFZRN

🧫Dr. Sandra Petrus-Reurer's team at NIHR Cambridge Biomedical Research Centre used co-cultures and humanized mouse experimental models to examine autologous and allogeneic immune responses to human primary cholangiocyte organoids as treatment for bile duct disorders. Cell Reports Medicine | bit.ly/3IxJtT0

👀 Dr. Brian Hafler's team at Yale School of Medicine obtained viable short-interval postmortem human retinal tissue and generated human retinal organoids that contain electrophysiologically active neurons. Science Advances | bit.ly/4lDtUI6

Researchers led by Drs. Pranavkumar Shivakumar & Jorge Bezerra from UT Southwestern Medical Center show that modulation of TGF-β-dependent EMT regulates bile duct epithelial development. 🔓 More here: go.nature.com/4lCfVSF

🔉 Organoid researchers, check out this The EMBO Journal article about kidney organoids! Scientists established a chemically defined, serum-free protocol for prolonged culture of human fetal kidney-derived organoids in vitro. 💡 Learn more: bit.ly/3II8jzK

In this new Cancer Gene Therapy study, researchers found a link between APC mutation type, #organoid maturation, and FAP severity. They show that rapamycin rescues APC-mutated colon organoid differentiation. 🧫 More here: go.nature.com/4muH3TZ

Dr. Ann Parr and team developed 3D-printed #organoid scaffolds for transplantation using clinically relevant hiPSC-derived regionally specific spinal neural progenitor cells. U of M Neurosurgery 📖 Learn more about spinal organoids: bit.ly/44NljN2

This review summarizes recent protocols that have been developed to generate human microglial-containing cerebral #organoids, focusing on the methods used to assess the level of microglial maturation compared to their in vivo counterparts. 🧠 👉 bit.ly/4mbvL6z

There are only a few days left to submit your abstract for a chance to present your research to an international audience at Organoids Are Us 2025. 📆23 - 26 September 2025 📍Glasgow, Scotland Find out more about the invited speakers and program here: bit.ly/4lGeToY

🧫 Dr. Guebum Han and researchers at University of Minnesota developed 3D-printed organoid scaffolds for transplantation using clinically relevant human induced pluripotent stem cell-derived regionally specific spinal neural progenitor cells. 👉 bit.ly/44NljN2

🧫 This study introduces a colon organoid model valuable for studying colorectal cancer and developing new diagnostic, preventive, and therapeutic approaches to prevent or delay tumorigenesis in familial adenomatous polyposis patients. 👉 go.nature.com/4muH3TZ

🚨Become an expert on using #organoids in drug discovery with STEMCELL Technologies! Stay up-to-date with current applications, new products, insights from key opinion leaders, and more: bit.ly/3QSfIwU

🧫 Researchers employed a digital light processing system to perform 3D bioprinting of a DNA-silk fibroin hydrogel sustained-release system with BMSCs to construct millimeter-scale cerebral #organoids. Military Medical Research | bit.ly/472GNa4

👂 Scientists developed a cochlear organoid culture system using synthetic GelMA hydrogel, thereby accelerating organoid formation and facilitating the functional maturation of cochlear hair cells. ACS Nano | bit.ly/44SUHZS

🧫 Scientists developed a novel liver multilineage organoid model combined with Mdr2-/- mice to investigate the pro-fibrotic role of T helper 17 cells for primary sclerosing cholangitis. 🔓 Journal of Nanobiotechnology | bit.ly/4l8sgx1

🎯 Researchers developed CAR-T cells targeting B7-H3 and evaluated their anti-tumor activity in vitro and in vivo, using patient-derived organoids and xenograft models to validate their translational potential. British Journal of Cancer | go.nature.com/4fjx0yI

Researchers describe #organoid cultures derived from pig foliate taste papillae in which the cellular heterogeneity of the lingual epithelium is preserved. 💡 Learn more in Endocrine Society: bit.ly/4lgdTXE

Dr. Elly Hol's team at UMC Utrecht found that mutations in GFAP can severely affect neural #organoid development through altering lineage commitment in embryoid bodies. GFAP plays a role as an early modulator of neurodevelopment. 🧠 bit.ly/40PH6RS

How can intestinal #organoid models be used as tools to interrogate the physiology of human mucosal tissues and host-microbe interactions? 💡 Learn from this review: bit.ly/47kamnC

Using patient-derived #ColorectalCancer (CRC) organoids and functional assays, researchers investigated the role of stromal-secreted Wnt5a. Wnt5a suppresses CRC progression via TGF-β/NOTUM/OLFM4 axis in patient-derived #organoids. 👉 bit.ly/45pmnFF