very nice piece of work from Jamie Robinson. Like a dream come true. Hope PWCoCo can add value to future colocalizaiton analysis

Such a nice review lead by Venexia Venexia Walker 😀

We are pleased to announce that our height GWAS: A Saturated Map of Common Genetic Variants Associated with Human Height is published in nature today! This is a fantastic effort involving >600 GIANT consortium investigators and 23andMe.

So excited to see the flagship and 7 more GBMI papers online today. It’s such a honor to work with the great team led by @bmneale, @cristenw, Mark Daly, Alicia Martin coordinated by @sineadbchapman. Big thanks to biobanks and their participants for making our research possible.

New preprint available 🥳 (with Clara Albiñana, Bogdan Pasaniuc, Bjarni Vilhjalmsson) We present a new version of LDpred2-auto and validate it for inference of genetic architecture parameters. This figure gives a summary of what LDpred2-auto can give you now: 1/

Very nice piece of work from our brilliant PhD candidate Huiling Zhao Ling 🌟🌟🌟 Such an honour to be part of GBMI! Great honour to collaborate with big names: Ben Brumpton, Wei Zhou, Ben Neale and Tom Gaunt. Hope this will open the door for multi-ancestry proteome-wide MR.

A very nice conversation between Emma/Dylan and us was online in Diabetologia. Need to be very careful about what we are instrumenting when conducting drug target MR! link.springer.com/article/10.100… link.springer.com/article/10.100… Tom Gaunt george davey smith @emmylooroll Dylan Williams

Our paper "The association between genetically elevated polyunsaturated fatty acids and cancer risk" is finally out. Many thanks to my collaborators and co-authors! Will try to do a tweet thread in the near future. sciencedirect.com/science/articl…

Mendelian randomization suggests lower circulating sclerostin increases cardiovascular risk pubmed.ncbi.nlm.nih.gov/37096546/

Exciting fully-funded #PhD opportunities at the MRC IEU @Bristol_Uni Interested in #multiomics #pregnancy and improving #AntenatalCare? Apply by June 5th and get it touch to find out more findaphd.com/phds/project/u…

Our recent efforts try to use MR-Clust to distinguish pleiotropy of omega-3 fatty acids instruments. …nslational-medicine.biomedcentral.com/articles/10.11…

Taking a common diabetes medication after testing positive for SARS-CoV-2 reduces risk of developing #longCOVID by 40%, new study in The Lancet Infectious Diseases finds hubs.li/Q01SCsZj0

Thrilled to share that our work to explore the potential of metformin in longevity using genetics is now available at The Lancet Healthy Longevity sciencedirect.com/science/articl… Much appreciated Ryan Au Yeung Prof Ian Wong Celine Chui HKU Jie Zheng (Chris) Christine Yuan HUANG C Mary Schooling HKU Public Health HKU Medicine

Very interesting study found FTO variants rs1421085 T>C promotes brown fat thermogenesis, evidence from both human and mouse model.

#HKUSPH finds #metformin, an affordable medication for #type2diabetes, might promote healthy ageing using drug-target Mendelian randomization. @ShanLuo7 Ryan Au Yeung Prof Ian Wong Celine Chui HKU Jie Zheng (Chris) Christine Yuan HUANG C Mary Schooling Paper The Lancet Healthy Longevity: sciencedirect.com/science/articl…

My take on relationships between sclerostin and cardiovascular disease, and implications for selecting patients for Romosozumab link.springer.com/article/10.100…

Our protein-wide MR analysis reveals many blood proteins in the development of type 2 diabetes and complications. Now online in Cell Reports Medicine Link 🔗 cell.com/cell-reports-m… A happy journey of this work with Jie Zheng (Chris) Susanna Larsson

Mendelian randomization revealing the protective effect of sodium-glucose cotransporter 2 inhibition on prostate cancer with verified evidence from electronic healthcare and biological data medrxiv.org/cgi/content/sh… #medRxiv

Welcome to the 6th Sino-European lnnovation and Professiunal Devetopmment forum 2023. Three forum at Zurich, Lausanne and Helsinki mp.weixin.qq.com/s/4nHNzg8zUGdn… mp.weixin.qq.com/s/Wzp4ifmXzPc4… mp.weixin.qq.com/s/lkZcKZ23nhIu…

Our recent efforts that estimates the effect of protein levels of ABO on pregnancy related outcomes: a Mendelian randomization study medrxiv.org/content/10.110…