Popular methods like UMAP & t-SNE are stochastic and distort data structure. Bonsai - a novel method - builds trees to relate high-dimensional objects, accounting for measurement noise. biorxiv.org/content/10.110…

Radical approach to the UMAP debate: offering an actual alternative

Bonsai: Tree representations for distortion-free visualization and exploratory analysis of single-cell omics data biorxiv.org/content/10.110…

New paper! Concentrations of active transcription factors (TFs) can fluctuate on the same time scale as individual TF binding and unbinding events, causing 'non-equilibrium' regulatory responses in their targets. We believe this may be pervasive in bacterial gene regulation.

Rash and premature, according to a spokesman of the Catholic Church .