Not forgetting we are also recruiting a computational post-doc to analyse single-cell data on our discovery that primate-specific ZNF808 is necessary for pancreas development: Job: jobs.exeter.ac.uk/hrpr_webrecrui… Paper: nature.com/articles/s4158… 5/

Two fantastic data science and AI roles are available to work with Nick Owens @uniofexeterHLS. A great opportunity to use computational methods to study gene regulation in disease. See the links for details: University of Exeter jobs.exeter.ac.uk/hrpr_webrecrui… jobs.exeter.ac.uk/hrpr_webrecrui…

Still time to apply for our #computational #postdoc studying primate specific ZNF808 in pancreas development using #singlecell #Genomics nature.com/articles/s4158… Job: jobs.exeter.ac.uk/hrpr_webrecrui…

Super pleased that two of our recent genetic discoveries have made it onto Dr. Veera Rajagopal's "Biggest Stories of 2023" list. Great work #TeamExeter 🤜🤛. @athattersley @DrElisaDeFranco Nick Owens Exeter Med School

Ailsa MacCalman is enhancing our understanding of disease & cell regulatory function. At #nanoporeconf, she'll discuss using direct #nanopore sequencing to investigate the co-operative binding of transcription factors at a disease locus. Learn more: bit.ly/3Lg2tDu

Thrilled to be speaking at the Nanopore Community meeting in September!

Our follow-up paper establishing non-coding cis-regulatory variants in HK1 cause #congenitalhyperinsulinism with variable disease severity is now available for download on Lancet preprints papers.ssrn.com/sol3/papers.cf…. A few spoilers in the thread below (1/4) SSRN @HIgenes

New research has found 4 genes with some of the largest known effects on timing of #menopause, providing new insight into links between menopause timing and #cancer risk. news.exeter.ac.uk/faculty-of-hea…

Genetic underpinnings of menopause age and connections with cancer risk, new mutations in children and reproductive longevity nature nature.com/articles/s4158… Anna Murray nature.com/articles/d4158… Anne Goriely Nature News & Views

ExWAS of age at menopause in ~100k women in the UK Biobank reiterates the important role of DNA damage response pathway in healthy ovarian aging. Great paper from a fantastic team of scientists. Article: nature.com/articles/s4158… News and Views: nature.com/articles/d4158…

Incredible few days at the Nanopore Community Meeting. Thank you to Oxford Nanopore for inviting me to talk about our work looking into base-pair level chromatin accessibility Nick Owens #nanoporeconf

Our work establishing the orphan nuclear receptor NR5A2 as an essential regulator of early mouse development is finally out! We show that NR5A2 is required for the development of a viable morula. doi.org/10.1126/scienc…