Voluntary headfixation that enables tracking of the same neurons across the lifespan of a rat! Amazing work, Dylan Rich! nature.com/articles/s4146…

How does the cerebellum distinguish between sensory feedback arising from our own motor actions versus unexpected external perturbations? In our recent paper, we unravel the intricate details of the processes that unfold in the anterior cerebellar vermis nature.com/articles/s4146…

Happy to share this Susanne Ahmari, MD, PhD 🔦🏠 work co-led by myself, Lizzie Manning and Britt Chamberlain, with critical help from Vijay Mohan K Namboodiri and @DrJamiePierson! We investigated how striatal spiny projection neurons contribute to compulsive grooming in Sapap3-KO mice. nature.com/articles/s4146…

Happy to announce that our paper on PdCO is finally out Nature Methods - check out this great tutorial by the awesome @JWietek:

I have been taking papers that seemed interesting from bulletin boards my whole career - this is what they were for in the math department. Are you telling me that people have been hanging up whole-ass papers for any other reason that to invite you read them?

Submitted my K99/R00 application today! Thank you to all those at UF and beyond who supported me in writing this application! 👩🏻‍💻🐊😊🎉

if you missed this webinar, it's now online! feel free to reach out with any questions.

My conversation with Science Magazine’s Christie Wilcox on 06.19✨ “By celebrating Juneteenth, we are honoring truth.” science.org/content/articl…

Excited to have Barbara in the lab now as a SNIP student! She has worked for us for about 2 years now as a volunteer, and will be joining the lab after the summer as a post-baccalaureate fellow.

Today we present precise detection of endogenous opioids using genetically encoded biosensors. Multiple early variants have been validated in labs, and we have now optimized, determined, and benchmarked the first-gen opioid sensors for both in vitro and in vivo applications.

we're just about halfway through #OptoGRC2024 and our community has been as inspiring as it has been transformative -- thank you to everyone from the bottom of my engram-filled heart 🧠 Ofer Yizhar 💔 Bianca Jones Marlin, PhD Denise J. Cai, Ph.D. Karl Deisseroth Optogenetics Gordon Research Conference!

New lab preprint from the outstanding postdoc Nicole Chambers, PhD! Here we report new exciting data from a model of GNAL linked #dystonia that we have created. Most importantly, this model shows overt dystonic motor phenotypes, a first for GNAL linked dystonia (1/N).

Rick's dedication to curing dystonia is inspiring, and he will soon be a published expert in the disease that he and Tyler's Hope is dedicated to curing.

If you’re still here at Society for Neuroscience (SfN), come and see posters from Mark Moehle Lab ! This morning Iggy presents electrophysiological and cognitive changes in the PFF model of PD and this afternoon I will present electrophysiology and behavioral data from our Gnal linked dystonia mouse.

In this new preprint, Emily Twedell (PhD student) and colleagues identify a functional role for the inhibitory synapses between striatal projection neurons -- shaping striatal ensembles to promote healthy action selection. biorxiv.org/content/10.110…

givingday.ufl.edu/campaigns/uf-e…

Congratulations to our incredible FLORIDA College of Medicine faculty recognized as outstanding or rising star researchers and mentors at the 15th Annual #UFMedResearch Celebration! Meet the winners: news.drgator.ufl.edu/2025/02/07/uf-…. #GoGators

Congrats, Mark!! Well deserved! I’m excited to be among those in Mark Moehle Lab who are presenting research at UF Medicine Celebration of Research tonight from 5-7.

Pathological α-Synuclein Perturbs Nuclear Integrity biorxiv.org/content/10.110… #biorxiv_neursci