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💫NEW: Steven Sloan, Caitlin Sojka & co analyse the transcriptomic & epigenomic landscape of human #astrocyte maturation and identify an epigenetically regulated intermediate state linked with aberrant development in #glioblastoma. 👉🏾rdcu.be/eayMF nature.com/articles/s4155…

💫NEW: Brumbaugh Lab, Dempsey & co show that #H3K36 methylation maintains #intestinal epithelial fate commitment, whereas its suppression induces a plastic state and expression of genes involved in #regeneration. 👉🏿rdcu.be/eayN3 nature.com/articles/s4155…

☕️Ma et al. show that heterogeneous nuclear ribonucleoprotein U promotes the primed state in human #pluripotent stem cells by interacting with #NuclearMatrix protein, Matrin-3, and regulating primed-specific genes. 👉rdcu.be/ebq0W bit.ly/4kfVwT8

☕️Fulcher et al. show that #MDM2 times mitosis through self-catalysed ubiquitination and proteasomal destruction, triggering G1 arrest following delays in #mitosis associated with chromosome instability and #aneuploidy. bit.ly/3EUEc66

☕️Jingtao Guo, Leqian Yu & co characterize an intact Carnegie stage 7 #HumanEmbryo at single-cell resolution in a spatially resolved manner. 👉🏻rdcu.be/ebq3Q bit.ly/3XhKW48

☕️Interested in how cells respond to #mitochondria #ProteinImport stress? Read our Review article by Nikolaus Pfanner, Fabian den Brave & Thomas Becker. 👉🏽rdcu.be/ecb3x bit.ly/41oGhyD

☕️Wang et al. profile the #translatome of #hematopoietic #StemCells (HSCs) and downstream progenitors and lineages. They identify the SNORD113–114 cluster as a modulator of translation and self-renewal in HSCs. 👉🏿rdcu.be/ecb3W bit.ly/4i2xxVX