We are happy to report our dream aldol reaction! @sciencemagazine This project took literally a decade to come to fruition and tonight we celebrate our star graduate student Lucas! science.sciencemag.org/content/362/64…

Ten simple rules for developing good reading habits during graduate school and beyond dx.plos.org/10.1371/journa…

“The code of life is like Beethoven’s Symphony - it’s intricate, it’s beautiful. But we don’t know how to write like that.” In her Nobel Lecture Frances Arnold explains how nature’s process - evolution - helped her in the lab. Watch the full lecture: youtu.be/6hOZ5e0g9Uo

Rapamycin-inspired macrocycles with new target specificity | Nature Chemistry nature.com/articles/s4155…

Chirality resolved: research in Nature shows it’s possible to convert racemic mixtures to a single enantiomer using light-activated catalysts. go.nature.com/2RXsLNA

THIS! And learn from #ChemNobel Prof Barry Sharpless "I always wore glasses whenever I was at my bench, and while I felt I conscientiously observed safety measures, my experience proves one can't be too cautious about wearing safety glasses." #ChemSafety news.mit.edu/1992/safety-03…

We are hiring! Postdoctoral candidates interested in working on medicinal chemistry at the BU-CMD can check out this link for more details. bu.edu/cmd/contact-us… #chemjobs

Hill lab still looking for post docs! Please apply! See website for details.

A biosynthetic pathway that makes amino acids containing terminal alkynes. Because such functional groups are rare in natural products, they provide a handle for chemistry that’s not generally found in biological organisms. Via @nature ow.ly/pf7330o2hf9

From Suzanne Walker’s lab: Dr. Cassie Joiner and Zebulon Levine discovered that “Aspartate Residues Far from the Active Site Drive O-GlcNAc Transferase Substrate Selection” Very excited that @drcmwoo & I were able to help with Glycoproteomic exp! #IsoTaG :) pubs.acs.org/doi/10.1021/ja…

Going to #ACSSanDiego? Christina Woo @drcmwoo MCB_Harvard will hold a lecture on Wednesday sponsored by ChemBioChem #ChemBioTalents at the symposium organized by Matthew Pratt @PrattLabUSC She coauthored an Angewandte Chemie paper: onlinelibrary.wiley.com/doi/10.1002/an…

Also, learn how to get a high without using opioids in this epic opioid GM. (Hint: exercise required) baranlab.org/wp-content/upl…

I’ve written this letter to draw attention to media establishments that have been publishing and broadcasting the victim’s photos and videos of her bodily remains. It is unethical and downright disgusting. Share and retweet if you agree.

Whether it is #PriyankaReddy in Hyderabad, #Roja in Tamil Nadu or the law student gangraped in Ranchi,we seem to be losing it as a society. It has been 7 yrs to the gut-wrenching #Nirbhaya case & our moral fabric continues to be in pieces.We need stricter laws.This needs to STOP!

Beyond PROTACs and the proteasome: broadening the TAC toolbox biocentury.com/article/304406 There's a TAC for everything

You may have heard about the massive number of COVID-19 tests being run as colleges try to bring students back to campus. These “rapid” antigen tests provide results in 15 min, but how does that work and is it as good as the RT-PCR test? A #SciCommSunday thread.

Congratulations to team Saki Hope Flaxman @Big_Fish_Linda nandini v Hannah Dacheng and collaborators Matt Pratt and Binyou! This was a true collaborative effort in the group to discover a degron for cereblon! rdcu.be/cXTkl

Nature research paper: The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron go.nature.com/3TgYM2U

It's finally here! We developed a molecular glue that degrades IKZF2 and CK1 alpha and kills leukemia cells. @drcmwoo and I had an awesome time collaborating with Sun Mi Park and Michael Kharas MSK! authors.elsevier.com/c/1gjK-5TA51da…

First publication into a new field of study! I hope the opioid field begins to appreciate the different chemistries and interactions opioids can possess. Other exciting developments are on the way! 🍳 Chemical tools for the opioids sciencedirect.com/science/articl…