🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Birgitta Henriques-Normark and colleagues use Grad-Seq to probe RNA-protein interactions in gram-positive bacteria #MTCPubs embopress.org/doi/full/10.15…

Trouble getting huge plasmids into cells? Claudia Kutter and colleagues describe a method which makes this infinitely easier! #MTCPubs nature.com/articles/s4200…

Elena Kashuba and colleagues describe that the ribosomal protein S18-2 promotes cell stemness #MTCPubs pnas.org/content/117/27…

Yihai Cao and colleagues demonstrate that concomitant targeting of VEGF and PDGF can inhibit growth of FGF2+ cancers #MTCPubs nature.com/articles/s4146…

Yihai Cao and colleagues use zebrafish to visualise how human cancers are killed! #MTCPubs pnas.org/content/117/37…

Our work on ”Regulatory RNA and its association to invasive meningococcal diseases” is now out in The Lancet Microbe . 😊Our SEM picture is the cover picture too. Very proud of the group! Jens Karlsson @strategiskaSSF KAW Karolinska Institutet @MTC_KI thelancet.com/journals/lanmi…

Galina Selivanova and colleagues publish that p53 activation can boost the immune response to cancers! @MTC_KI #MTCPubs cancerdiscovery.aacrjournals.org/content/early/…

Mobile elements constantly remodel genomes. Here, Claudia Kutter et al. show that transposons give rise of new tRNA genes to improve translation efficiency. #MTCPubs @MTC_KI academic.oup.com/gbe/article/13… academic.oup.com/gbe/article/13…

Anders Björkman and Ulrika Morris provide an explanation for intriguing recent findings of frequent asymptomatic P falciparum malaria infections in areas with low herd immunity @MTC_KI #MTCPubs cell.com/trends/parasit…

Long noncoding RNAs remodel molecular responses. Here, Claudia Kutter and colleagues found that the oncogenic LINC01268 promotes liver cancer via MAPK/NFkB signalling. #MTCPubs @MTC_KI dovepress.com/high-expressio…

Immunoglobulin germline genes exhibit extensive allelic diversity between individuals. Karlsson Hedestam Lab and colleagues characterise this diversity in macaques to provide insights into Ig loci evolution and the development of antibody responses. @MTC_KI #MTCPubs cell.com/immunity/fullt…

Maria Ruiz Perez and colleagues show that neuroblastoma, which originates from embryonic precursor cells, undergoes neural differentiation upon inhibition of fatty acid synthesis, a metabolic pathway frequently activated in human cancer. @MTC_KI #MTCPubs cell.com/iscience/fullt…

Manuel Patarroyo and colleagues demonstrate a role for laminin alpha 5 in mammary gland remodelling. @MTC_KI #MTCPubs …urnals-biologists-com.proxy.kib.ki.se/dev/article/14…

Paper alert - Maria Johansson and colleagues show that mouse NK cell inhibitory receptor repertoire skewing is observed already in bone marrow and propose a model for how repertoire skewing is established. #MTCPubs journals.aai.org/jimmunol/artic…

Ute Römling and colleagues show that a single amino acid substitution Q329R in the patatin-like phospholipase CapV leads to functional plasticity, which consequently transforms cell morphology and bacterial physiology #MTCPubs nature.com/articles/s4152…

Balanced anticodons-codon pools control translation. At the single cell level, Claudia Kutter and colleagues found that most cell types exhibit even anticodon-codon pools but increased translation efficiency in neurons. #MTCPubs genome.cshlp.org/content/32/1/9…

New roles of noncoding RNAs in cancer cells are uncovered. Here, Claudia Kutter and colleagues show that LINC00326 interacts with a noncanonical #RBP to impair liver cancer cell growth by altering lipid metabolism. #MTCPubs gut.bmj.com/content/71/10/…

Marie Arsenian-Henriksson and colleagues show that a combination therapy that activates three nuclear hormone receptors (GR, ERα and RARα) leads to neural differentiation, metabolic reprogramming and reduced tumour burden in neuroblastoma #MTCPubs jeccr.biomedcentral.com/articles/10.11…

In this review, Marie Arsenian Henriksson and colleagues discuss the potential of mitochondria as a target for precision medicine in cancer, presenting current inhibitors and challenges, and highlighting those enzymes that are attractive targets. #MTCPubs nature.com/articles/s4141…

From Karlsson Hedestam Lab lab - Personalized immunoglobulin genotyping coupled with monoclonal antibody engineering identifies germline-encoded polymorphisms that influence our anti-viral B cell response. @MTC_KI #MTCPubs doi.org/10.1016/j.immu…