We have multiple postdoc positions available in my group at NYU. Join us if you're interested in complex trait genetics and biology. More information about the lab on our website: mostafavilab.org med.nyu.edu/research/postd…

We are recruiting postdoctoral fellows! Interested in using quantitative tools to study gene regulation in stem cell-derived developmental models? See below for more info and reach out

Excited to share the last paper from my PhD, advised by @spence_jeffrey_ and Jonathan Pritchard! We explore a new way to study selection on complex traits that circumvents some of the most troublesome limitations of GWAS biorxiv.org/content/10.110… (1/9)

Delighted to announce that I will be joining the Department of Molecular & Cellular Biology at Harvard University MCB_Harvard Harvard University as an Assistant Professor this August: mcb.harvard.edu/department/new… The Nagashima lab is interested in immunology, microbiome, and diet. We attempt

Thrilled to share the bulk of my PhD work, now up on bioRxiv! This project brings together aspects of network theory, systems biology, and single cell genomics, towards understanding properties of gene regulatory networks (GRNs). Read on for more —> (1/) doi.org/10.1101/2024.0…

HLA is the locus that everyone loves to hate, so it rarely gets invited to the GWAS party... There’s good reason for this. The region has extensive LD, high gene density and high polymorphism. (Thread + preprint link below ⬇️) (1/8)

The Nagashima lab MCB_Harvard seeks an ambitious postdoc in immunology, microbiome and diet. Apply here👇 if you want to work on T cell biology in an incredible environment. academicpositions.harvard.edu/postings/13926 Harvard University #immunology #microbiome #postdoc

🚨New Preprint Alert: Our work led by Jinghui Li is up on bioRxiv. We re-analyzed large maps of trans-pQTLs, and found that protein–protein interactions shape trans-regulatory impact of genetic variation on protein expression and complex traits. A brief thread🧵👇

BREAKING NEWS The Norwegian Nobel Committee has decided to award the 2024 #NobelPeacePrize to the Japanese organisation Nihon Hidankyo. This grassroots movement of atomic bomb survivors from Hiroshima and Nagasaki, also known as Hibakusha, is receiving the peace prize for its

#ASHG24 folks, I’m giving a talk on Nov 6 on the fundamental differences in gene discovery with common vs. rare genetic variants. Hope to see you there!

For many traits there is a correlation between the number of duplications or loss-of-function (LoF) mutations someone carries, and their phenotype. Curiously, for most traits, these effects are aligned in the SAME direction. Why?

In a new preprint led by Nikhil Milind, we explored a fascinating paradox: For many traits the number of duplications or loss-of-function (LoF) mutations is correlated with phenotype. Curiously, for most traits, the AVERAGE direction of LoFs and Dups is the SAME. Why?

Excited to share the latest from the @MarsonLab! An investigation of context-specific gene regulation in T cells, which led to dynamic mechanisms required to control T cell rest and activation. Published today in nature thanks to the work of many! nature.com/articles/s4158…

In a country where women's voices are silenced, a young Iranian woman, Parastoo Ahmadi, held an 'imaginary' concert. Fearless of the punishment that awaits, she sang and inspired the dream of a free Iran. A true symbol of resistance. Full video here: youtu.be/oYcaDHEnhbU?si…

New approach to discovering the biology of GWAS signals “by combining quantitative estimates of gene-trait relationships from loss-of-function burden tests with gene-regulatory connections inferred from Perturb-seq experiments in relevant cell types.”

I'm delighted to present our nationwide effort to identify genetic determinants of child health and development in Japan. medrxiv.org/cgi/content/sh…

It was fun writing this short piece on the omnigenic model. Sharing it here, though it's a painful time as my family, along with millions of others, is at risk in Iran and the region.

留学から帰国された太田峰人先生に、留学中の生活と研究について講演していただきました！