Lina Sui reports major new insight in cell differentiation. Establishing cell-intrinsic limitations in cell cycle progression controls graft growth and promotes differentiation of pancreatic endocrine cells biorxiv.org/content/10.110…

biorxiv.org/content/10.110… Dr. Lina Sui keeps moving the field forward! "Establishing cell-intrinsic limitations in cell cycle progression controls graft growth and promotes differentiation of pancreatic endocrine cells"

One can never be too careful with their interpretations. Some uncertainties worth figuring out about the recent human embryo editing paper x.com/biorxivpreprin…

Great post! Really hoping the sequencing data tell the full story. Inter-homologue repair in fertilized human eggs? biorxiv.org/content/early/…

All valid points in this rebuttal! How could reviewers not see that? x.com/tcomplex/statu…

Beyond hype: #preprint post-publication peer review of human gene editing paper raises important questions #bioRxiv biorxiv.org/content/early/…

Doubts emerging on Mitalipov lab #CRIPSR human embryo Nature paper ipscell.com/2017/08/doubts… … & see preprint biorxiv.org/content/early/…

Doubts raised on key points of Nature paper on CRISPR gene editing of human embryos ipscell.com/2017/08/doubts… via paulknoepfler

Skepticism surfaces over CRISPR human embryo editing claims sciencemag.org/news/2017/08/s…

Wow! Really great stuff! #Beta-Cell Replacement, Type 1 #Diabetes #NuclearTransfer #Embryonic #StemCells diabetes.diabetesjournals.org/content/early/…

Nice short thread highlighting a follow-up paper on the heavily publicised paper that used CRISPR to correct a dominant mutation in human embryos. I remember a lot of people keen to retweet the awesomeness (incl. myself). N.b. caution is advised before boarding the hype train. x.com/GaetanBurgio/s…

New study finds generally opposite gene editing results/mechanisms to that reported in sexy Ma Nature paper on #CRISPR in human embryos last year that had argued for inter homolog repair but came into some doubt after Egli, et al. preprint x.com/GaetanBurgio/s…