.Daniel Michelson, Mathis et al. Harvard Medical School show that the transcription factor Hnf4 upregulates gut and liver self-antigens within thymic epithelial cells via an enhancer-driven mechanism, mirroring peripheral development within the thymus bit.ly/3ri9opa

Thanks Vanja Cabric & Chrysothemis Brown for this lovely perspective on our recent paper. Much more to learn about mimetic cells and Aire, inside and outside of the thymus!

We are very happy to share our lates publication in nature, spearheaded by Tal Givony &Yael Goldfarb, expanding the incredible cellular & functional diversity of mTECs and bringing key insights into the roles of thymic microfold and endocrine cells nature.com/articles/s4158…

New in Science Immunology: we provide a multi-pronged dissection of muscle inflammatory responses to acute and chronic endurance exercise and uncover a critical role of Tregs in restraining such responses to promote enhanced performance after training. shorturl.at/cfTX0

Out today in nature, we describe HHV-6 reactivation in T cells, including therapeutic CAR T cells. I’m so grateful to have worked with an all-star team during my time in the Ansu Satpathy lab that led to these findings. nature.com/articles/s4158… 1/n

Happy to report that the final peer-reviewed version of my main postdoc paper is now out in Science Immunology Science Immunology (1/7): science.org/doi/10.1126/sc…

Excited to show our recent work regarding meningeal T regulatory cells and their role preserving hippocampus stem cells!

Watch this space — big things to come from the Muñoz-Rojas lab!

Check out this illuminating💡⚡️work from Kaitavjeet Chowdhary on the genomic wiring of Tregs! Some amazing insights including the fact that not all Tregs need FoxP3🤯🤯

Poison exons and gating of TCR signaling — such a cool connection from Tima Karginov between the bleeding edge of molecular biology and immunology!

Glad to share our latest thoughts on thymic mimetic cells, situating them within wider currents of molecular, cell, developmental and evolutionary biology: doi.org/10.1146/annure… Thanks Annual Reviews Ruth Lehmann for the chance to contribute to a diverse and fascinating volume!