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💥💥💥 !!! Please re-post !!! 💥💥💥 Hello Community, We’re excited to announce that we’re moving to Groningen in January 2025 to embark on a new chapter in our research careers. For this, we need a house/flat and we hope to find a nice place with your help.

Leveraging engineered #Pseudomonas putida minicells for bioconversion of organic acids into short-chain methyl ketones by Ekaterina Kozaeva, Manuel Nieto-Domínguez, Max Stammnitz @maxstammnitz.bsky.social et al. ACS Synthetic Bio Nikel SEM Group DTU Biosustain #OpenAccess pubs.acs.org/doi/10.1021/ac…

Biochemical and structural characterization of the full-length CdaA reveals that efficient synthesis of the second messenger cyclic di-AMP requires membrane-bound cyclase enzyme. nature.com/articles/s4200… Cristina Paulino @DrougkasP Membrane Enzymology

Amazing tool for multiple cycles of genetic engineering of Gram negative bacteria developed by Filippo Federici and Francesco, now fully available! Nikel SEM Group

Our paper on single-molecule studies of enhanced enzyme diffusion (EED) is out - we use mass photometry to show that some enzymes dissociate to their subunits upon ligand binding, providing a possible mechanism for the previously observed EED. Saniye Gül Kaya pubs.acs.org/doi/10.1021/ac…

Engineering a phi15-based #expression system for stringent #gene expression in #Pseudomonas putida—led by Eveline-Marie Lammens, Daniel Volke in a nice collab between Nikel SEM Group & Rob Lavigne's team nature.com/articles/s4200…

Check out this fantastic symposium on structural biology held in beautiful Copenhagen.

Preprint alert🚨Systematic #engineering of synthetic serine cycles in #Pseudomonas putida uncovers emergent topologies for #methanol assimilation · bioRxiv led by Òscar Puiggené González #SynBio #Methylotrophy #CircularEconomy Nikel SEM Group biorxiv.org/content/10.110…

Glad to see my main PhD project finally out Nature Microbiology nature.com/articles/s4156… We show for the first time that a synthetic and engineered pathway can indeed exceed nature at one-carbon fixation.

Really happy to share that our work on constructing six glyoxylate / glycolate sensors covering a three order of magnitude concentration range is out now in Nature Communications ! 🔥 Read below to see how we developed the sensors and what they are good for 🥳. nature.com/articles/s4146…

Streamlined and efficient genome editing in #Cupriavidus necator H16 using an optimised SIBR-Cas system—spearheaded by @dellavallesimo & Enrico Orsi & led by Costas Patinios + Wei Huang Trends in Biotechnology #SynBio sciencedirect.com/science/articl…

PhD position available ASAP (in Dusseldorf, Germany) GASB SynBio

Ins and outs for designing bacterial metabolisms for C1-assimilation, from a multilevel perspective, now pieced together in this review from our Nikel SEM Group! Check it out at academic.oup.com/femsre/advance…

🌱💧 TOLERATE EU Project featured at #SFN & #Microbio25! Showcasing drought-resilient biobased solutions & connecting with the biotech community. 🔗 tolerate-eu-project.com

I'm truly excited to announce our new publication in nature unraveling a central picture of the Methyl-coenzyme M reductase (MCR) activation machinery and it's strong ATP dependency - kudos to Anuj Kumar for the fantastic illustration! LINK: nature.com/articles/s4158…

Next we have Sebastian Wenk with the Evolution-assisted engineering of formate assimilation in Escherichia coli #synbionl2025

🆕 New from TOLERATE: What can ancient climates teach us about today’s challenges? Discover how the past helps shape future climate resilience. 🌍 Read more 👉 lnkd.in/dE5CvEfp A special thank you to Amedea Perfumo –AWI- for this thoughtful contribution! #TOLERATEProject

🚨#LLPS: New trick for an old membrane protein! Homo- and hetero-condensates of a native membrane protein in E. coli tagged with PopTag 🔬🦠 LacY-PopTag is functional and localizes at cell poles or mobile foci in a curvature-dependent manner 🔗doi.org/10.21203/rs.3.…

🚨 New article! Discover how #TOLERATE uses ancient DNA & synthetic biology for #climateresilience & innovation. 👉 lnkd.in/dCx9bzuy #HorizonEU #EUResearch

New paper from the lab from @SriramGarg. We introduce a general substitution matrix for structural phylogenetics. I think this is a big deal, so read on below if you think deep history is important. academic.oup.com/mbe/advance-ar…