A serendipitous finding , reported by 1999 Tsien and colleages in 1999, led to the notion that fluorescent proteins can be turned into biosensors. 🧵with a bit of biosensor history ⬇️ pnas.org/doi/10.1073/pn…

My latest research is on bioRxiv now! Proud to present the amazing OPC Ca2+ dynamics in the cortex that’s not known to us till now. NE plays a surprising role in driving those beauties! Thanks Eric Hsu I’m also on the market now. Plz rt! #glia

The indefatigable Clara María Bacmeister has done it again. Thrilled to share our latest work out online today Nature Neuroscience! Stay tuned for the thread "Motor learning drives dynamic patterns of intermittent myelination on learning-activated axons" rdcu.be/cWFPH

Yahoooo! We did it! Mil gracias to all involved: Rongchen Huang & her epic surgeries; Lindsay Osso's indispensable input during reviews; Michael Thornton, Lauren Conant, and Anthony Chavez for their support throughout; and Alon and Ethan Hughes for stellar mentorship. Proud of us!

If you haven’t checked out my paper yet, now is the time ☺️

I am so happy to finally share the main work from my PhD on Polycomb-mediated genome folding: biorxiv.org/content/10.110…

“We’re trying to make transformational changes to our working conditions that will in turn impact the quality of research and education,” said Sweeney, the union leader. “The issues we face are similar to other workers in this country.” #FairUCNow washingtonpost.com/business/2022/…

The re-reconquista continues. Crucially, if France win this sets up a rematch of the critical Battle of Tours in 732.

I am thrilled to announce that I have been recruited to the University of Colorado Medical school (@CUAnshutz) as the new Chair of the Department of Physiology and Biophysics! And we are hiring! If you want to join our vibrant faculty, apply by Feb 15: cu.taleo.net/careersection/….

"State of the Lab" address returned today! It was great to revisit and celebrate the accomplishments of our talented group members 🎉 and pull back the curtain on the inner workings of the lab 👀 Onward and Upward!

Here is my graduate work exploring what determines oligodendrocyte sheath number! 🙂 Early myelination involves the dynamic and repetitive ensheathment of axons which resolves through a low and consistent stabilization rate doi.org/10.7554/eLife.…

Happy to announce that my fantastic student Dylan Calame's thesis work is out. Purkinje cells, learning, basis sets and more! For details, read paper here: nature.com/articles/s4159…

Huge congratulations to Michael Thornton for successfully defending his PhD thesis!!! Stay tuned for more of his amazing work coming soon 😎

Michael Thornton turned dreams into reality in his PhD work that is now up on BioRxiv! Stay tuned for more details 🔬🐭🧠 biorxiv.org/content/10.110…

Check out our new preprint, where we found some cool insights about remyelination. It was awesome to collaborate with Lindsay Osso, denmanlab and Autobahn Therapeutics in this project!

Dreams became reality through Michael Thornton tremendous PhD work! Thrilled this phenomenal collaboration with CU Neurophotonics Restrepo Lab is out in the wild. Looking forward to helping others leverage the powers of long-term three-photon microscopy 💪🏼🤓🔬

Folks at the CAN ACN meeting, come check out my poster today on in vivo imaging of endogenous and therapeutic-induced remyelination and its impacts on visual neuronal function!

Extremely excited to share our review on mature myelin dynamics out today! Ethan Hughes and I discuss myelin remodeling and turnover, mechanisms and functional implications. I hope folks will enjoy diving into this fascinating emerging field with us! nature.com/articles/s4159…

Excited to share our work published this week! Led by myself and world class co-first Gustavo Della Flora Nunes working in the Ethan Hughes in collaboration with Dan Denman: nature.com/articles/s4146…. A short 🧵

Extremely happy to share our manuscript jointly authored by me and the amazing Lindsay Osso ! An awesome collaboration between the Ethan Hughes , denmanlab and Autobahn Therapeutics nature.com/articles/s4146… 🧵