This media-independent method may open a new avenue for directing MSC differentiation in regenerative medicine. Scientists introduce interfacial silicification, which induces #MSC osteogenic differentiation without the need for BMP-2 and dexamethasone. bit.ly/4kJByze

Scientists including Dr. Franck Dequiedt and Bartimée Galvan reported that independently to its canonical roles in transcription, EWSR1::FLI1 also functions as an mRNA decay factor, reshaping mRNA stability in #EwingSarcoma. 💡 go.nature.com/4lY8Wnz

Learn with Dr. Guilin Tang from the MD Anderson Cancer Center (MD Anderson Cancer Center) as she takes you through her lab workflow, from plasma #CellIsolation to FISH assays, when performing cytogenetic analysis of plasma cell neoplasms. STEMCELL Technologies bit.ly/4f0w4yR

This study provides insight into the mechanism of action of #BPA and elucidates its impact on the functionality of MSCs isolated from the amniotic membrane of the human term placenta. 💡More in CDD press: go.nature.com/4o1ocBn

Findings from this research out of Tongji University indicate that #MSC-derived apoptotic bodies have the potential to be a promising and effective acellular therapeutic option for treating #MyocardialInfarction. 🔎 Take a closer look: bit.ly/4o3BA85

#MesenchymalStemCells have emerged as pivotal tools in biomedical engineering. 🔬 Read about current advancements in #photobiomodulation technology and its application in research below. 👇 bit.ly/4lJNHFT

Taking the tooth as a model organ, scientists employ ssRNA-seq to dissect the cellular composition and heterogeneity of human dental follicle and dental papilla, revealing a distinct #MSC population with remarkable odontogenic potential. 🦷 Give it a read:

Bmi1 modulates the neural differentiation of MSCs through its regulatory effects on Wnt3a and RhoA expression, thereby influencing the reparative potential of #MSCs in ischemic brain tissue. Read the paper out of Chinese Medical University. 👇 bit.ly/3GW4IgT

Researchers including Joaquin Olmedo-Pelayo report a novel mechanism of sensitivity to DNA topoisomerase 1 poisons in #EwingSarcoma. They demonstrate the impact of a dominant mutation on cancer drug sensitivity. 💊 go.nature.com/3IScFEn | Oncogene Journal

Adjusting chitosan’s chemical properties can promote specific lineage differentiation and enhance #MSC immunomodulatory functions, vital for therapeutic efficacy in inflammatory conditions. 💡 Read the review: bit.ly/45tdo7G

Dr. Hongqi Zhang and team assessed alterations in the mRNA and protein levels of genes linked to the differentiation of bone marrow #MSCs using samples taken from #congenital scoliosis. 🧬 💡 Read their findings in Scientific Reports: go.nature.com/46wHRCV

New in CDD press!💡 This study investigated the metabolic reliance of #osteosarcoma stem cells and related genes through in silico analyses of clinical osteosarcoma specimens and in vitro and in vivo genetic and pharmacological analyses. go.nature.com/41l6saj

Researchers demonstrate the safety and tolerability of #MSC therapy in patients with decompensated liver #cirrhosis and provide the first human-based evidence on the dose‒effect relationship and optimal administration regimens. 💊 🔗 go.nature.com/3HheCcS

Researchers treated #MSCs with poly-L-lysine-modified magnetic nanoparticles (MNPs) and evaluated the effects of MNPs on the biological functions of MSCs, including cell viability, directed differentiation, proliferation, and cytokine secretion. 🔓 go.nature.com/3GYNVKd

Researchers from Capital Medical University developed a human dental pulp stem cell injection to promote periodontal regeneration through a non-invasive procedure. 💉 🦷 Read their findings: go.nature.com/45C7UYh

Scientists including Dr. Hongqi Zhang assessed alterations in the mRNA and protein levels of genes linked to the differentiation of #BMSCs using samples taken from #CongenitalScoliosis. 🧬 💡 Check it out in Scientific Reports: go.nature.com/46wHRCV

Scientists including Dr. Dror Seliktar developed an interpenetrating polymer network #hydrogel for the 3D culture of multipotent #MSCs. Check out the team's study published in ACS Biomat Sci & Eng. 👇 bit.ly/4mCT1uM

🦴 E7 peptide-functionalized coaxial fiber membranes effectively facilitated bone defect repair by promoting the recruitment and osteogenic differentiation of BMSCs, demonstrating substantial potential for tissue engineering applications. 🔗 bit.ly/3UoH5k5

🧫 Scientists clarified the trained-human bone marrow mesenchymal stem cells in restoring the tissue immuno-microenvironment in fulminant hepatic failure mice. 👉 links.stemcell.com/3HkQiHi

🧪 Investigators developed a 3D-printed gelatin methacryloyl scaffold loaded with hydrogen sulfide-preconditioned MSC-derived extracellular vesicles to promote motor function recovery in spinal cord injury. 👉 ACS Biomat Sci & Eng | bit.ly/3HdN2gV