Congratulations to Liz and Shauna @paradinelab! Unique catalyst effects explored in a HBD-catalyzed enantioselective synthesis of homoallylic amines. Check it out in J. Am. Chem. Soc. ASAPs. pubs.acs.org/doi/10.1021/ja…

This project was still in its infancy when I first saw Hayden and Jake present on it, and it’s been really cool to see how the story has evolved over the past couple of years! Congrats guys!

Congrats to Dennis Kutateladze on his publication in JACS! Rationally optimized hydrogen-bond donors work in concert with cat HCl to promote a highly enantioselective Prins cyclization. Stay tuned for the unexpected origins of 100-fold rate acceleration! pubs.acs.org/doi/10.1021/ja…

Check out our most recent collaboration with Leibfarth Research in Science Magazine! It's the debut of our "dummy reagent" for diversification of aliphatic C–H bonds, featuring some awesome work by Tim Fazekas, Jill W. Alty, Eliza Neidhart, and Austin Miller. science.org/doi/epdf/10.11…

Check out our latest ChemRxiv manuscript by Katherine Forbes on the catalytic, enantioselective synthesis of stereogenic-at-P(V) building blocks and their diversification to a number of interesting products! doi.org/10.26434/chemr…

First work of my PhD now out on Chemrxiv! SFC-MS enables rapid measurement of ees from pooled crude reaction mixtures, allowing us to assess the generality of reported catalysts for the Pictet-Spengler reaction -- thanks Merck for a fun collaboration. chemrxiv.org/engage/chemrxi…

So excited to see all of the discoveries that come out of the Gair lab!

Huge congratulations to Katherine Forbes -- the Phosphorus queen -- on her publication in Science Magazine! Catalytic, enantioselective synthesis of stereogenic P(V) compounds through a key chlorophosphonamidate intermediate. science.org/doi/10.1126/sc…

Congratulations to Qiuhan, Sam Levi, Corin Wagen, and Alison Wendlandt on their publication in nature! Bis-thioureas engage biomimetic C-H pi interactions to catalyze highly site- and stereoselective glycosylation of unprotected sugar nucleophiles. nature.com/articles/s4158…

Such a cool approach to gamma C-H functionalization, and always happy to see new strategies that showcase the power of 1,6-HAT! Congrats to all!

Really delighted to see this tour de force in its final form! So many congratulations to this team!

Congrats to John Ovian, (Twitter-less) Petra Vojackova, and Jacobsen Lab for a magnificent study of a Ru/HBD co-catalyzed reaction, featuring some really funky catalyst effects. nature.com/articles/s4158…

How can one achieve high enantioselectivity (∆∆G‡=2.1 kcal/mol) in a nearly barrierless reaction (∆G‡<3 kcal/mol)? With Melanie Blackburn, I'm excited to share new work addressing this question in the context of protio-semipinacol rearrangements: chemrxiv.org/engage/chemrxi…

Boston EWOC community! Please join us for our Spring Kick-off event on May 2nd at Harpoon Brewery! Great opportunity to meet fellow EWOC members and allies, and enjoy a drink. Hope to see you there!

Very glad to see this in its final form! This was such a fun project to work on, and I’m so grateful to have been a part of team HCl with Corin Wagen, Raul, Pamela Tadross, Andrew, Dennis Kutateladze, and Jacobsen Lab!

🚀 The Gair group MSU Chemistry is about to launch! Seeking #Postdocs who are inspired by the shapes of molecules and driven to discover new molecular function that serves society. Apply here 🔗 bit.ly/3pKT9k2 to join our team!

Calling all Boston EWOC members and allies!! Please join us at Lamplighter Brewing in Cambridge, MA on August 2nd from 5-7 pm to socialize and more importantly, hear from our amazing guest speakers, Brenda Burke from Sanofi and Kathy Lee from Pfizer! Can't wait to see you all!

We're back with another Boston EWOC Happy Hour!! Come get to know your fellow EWOC members and allies at Craft Food Hall in Waltham, MA on 10/24 at 5:30 pm! Hope to see you all there!!