Goutham Sunny (@medoncodoc) 's Twitter Profile
Goutham Sunny

@medoncodoc

Academic account. Oncology & #medtwitter. Passionate about Preventive & community oncology, Big data, Computational onco and AI, Health economics, Med-Ed.

ID: 99938573

calendar_today28-12-2009 12:37:39

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🧬 Phase I Trial: Cisplatin + Berzosertib + Veliparib for DDR Disruption 📌 Objective: To potentiate cisplatin’s effect by inducing a BRCA-null–like DNA damage response (DDR) phenotype using berzosertib (ATR inhibitor) and veliparib (PARP inhibitor). 👥 Design & Regimen:

🧬 Phase I Trial: Cisplatin + Berzosertib + Veliparib for DDR Disruption

📌 Objective:
To potentiate cisplatin’s effect by inducing a BRCA-null–like DNA damage response (DDR) phenotype using berzosertib (ATR inhibitor) and veliparib (PARP inhibitor).

👥 Design & Regimen: