Delighted to share Laura Cacciaguerra et al #MOGAD epidemiology study: ➡️ 1st such population-based study in North America ➡️ Prevalence of 3.7/100K in Olmsted County & 2.61/100K in Martinique ➡️Trend towards increased incidence & recognition over time 👇 link.springer.com/article/10.100…

Had a great time on the Neurology Journal Neurology Podcast chatting about CSF correction factors for traumatic LP in adults! Hopefully a valuable discussion for those using these "rules of thumb" (e.g. subtract 1 WBC for every 1000 RBC) in clinical practice: youtube.com/watch?v=lihZod…

neurology.org/doi/10.1212/NX… Proud to share Stefano Masciocchi latest work on PLP1 antibodies in demyelinating diseases. PLP1 abs are mainly found in patients with non MS diseases with combined central and peripheral demyelination, but also in rare seronegative NMOSD

Our new CASPR2 paper is out ANA Journals 🤩 Headlines: Patients have neuropathic pain & fatigue as their main long term complaints which determine QoL. 😰 These are NOT immunotherapy responsive. 👩🏾‍⚕️💊 We also report other nuggets in this thread 🧵 ⬇️ onlinelibrary.wiley.com/doi/10.1002/an…

1/Do you have trouble keeping track of all the tractopathies? Wish you knew mo’ about mo’ tor neuron diseases? Read on for what you need to know in this months Radiographics review of motor neuron diseases! doi.org/10.1148/rg.240… Cooky Menias @RadG_editor RadioGraphics

Thanks for sharing our work on ‘CNS Tractopathies’ so nicely. This is often clinically challenging, given the broad differential diagnosis. We hope this article helps neurologists and neuroradiologists narrow down the diagnosis!

In 3 months (and zero days), we have the inaugural Mayo Clinic #florida #autoimmune #neurology meeting. 1.5 days of great speakers and 0.5 days to spend on the beautiful Jacksonville beach 🏖️ Please sign up now ✍️ ce.mayo.edu/neurology-and-… Mayo Clinic Neuro Dr. Alfredo Quiñones-Hinojosa

A 64-year-old woman presented with 18 months of progressive scalp-neck dysesthesias, left leg weakness, and urinary urgency. Read more: hubs.la/Q03hKGRg0 #NeuroTwitter #NeuroX

#CASPR2-#antibody diseases are provide clues to mechanisms of autoantigen-specific tolerance Here - in Science Advances - we show how central and peripheral B cell tolerance licences pathogenic CASPR2 antibody generation. science.org/doi/10.1126/sc… More below 👇🏿

Thrilled to share our recent study, which highlights the risk of false AChR-IgG positivity by RIPA in clinical practice 🎯 Paola Chessa Elia Sechi Valentina Damato 👏🏻 neurology.org/doi/10.1212/WN…

Delighted to share Cacciaguerra et al study ➡️ MRI guidelines in MS recommend 2 sagittal-T2 spine images but axial is optional ➡️ Here, axial-T2 found 2x more lesions vs sagittal ➡️ Thus, future guidelines should recommend both sagittal & axial images👇 link.springer.com/article/10.100…

Delighted to share our new study, led by @annacgeraghty and Lehi Acosta , uncovering the cellular dysregulation underpinning cognitive impairment after CAR T cell therapy and a strategy to rescue this cellular and cognitive dysfunction in mice. 1/ cell.com/cell/fulltext/…

MRI findings of genetic diseases often misdiagnosed as MS. A-D LHON B CADASIL. D CANVAS. E Krabbe disease F Cobalamin C disease. G polymerase gamma gene disease. H Alexander J/K CADASIL L Spastic paraplegia 5 with diffuse leukoencephalopathy pubmed.ncbi.nlm.nih.gov/40446704/

Great time celebrating Dr. Newman — our exceptional fellow in Autoimmune Neurology!

Happy to share Albert Aboseif et al multicenter study showing 4% of #MOGAD with meningitis ➡️ Frequent misdiagnosis as infection ➡️ Updates in criteria could incorporate this phenotype ➡️ Path had meningeal T & B cells, microglia & cortical myelin loss👇 jamanetwork.com/journals/jaman…

Dear Neurology Residents Starting in the ED Next Month, You will frequently encounter “?GBS” or “GBS rule out” consults. Please remember to carry your reflex hammer, save this post for future reference, and read the open-access review that I share ⬇️. 🤓 Since you won’t have

Happy to share Syc-Mazurek et al study of attack & remission MRI in #MOGAD vs #MS ➡️ Resolution of 1 lesion predicts #MOGAD and disappearance of ≥2 lesions separates #MOGAD completely from #MS ➡️ MRI 1 yr post #MOGAD brain/spine attack may aid diagnosis👇jnnp.bmj.com/content/early/…

In our recent study, the "Insular Knife Cut" Sign had 99.3% specificity for HSV encephalitis and was often detectable early after symptoms onset on brain MRI. An ominous sign not to miss in patients with suspected encephalitis of new onset!!! doi.org/10.1111/ene.70…

Who is a spectacularly good #antibody - #protein #biochemist? and wants to work on: 1. #Neuroimmune diseases 🧫 🧬 2. A translational environment @Mayo Clinic 🏥 🧑‍⚕️ 3. In Florida ☀️🏝️🏖️ 4. With an amazing lab team 👏🏼 If it’s you, please click here ⬇️ …wp-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candidat…

Applying the Supporting Features for MOGAD Diagnosis to Patients With Multiple Sclerosis | Neurology Neuroimmunology & Neuroinflammation neurology.org/doi/10.1212/NX… Pietro Zara Matteo Gastaldi Sara Mariotto Rosa Cortese Sara Carta and Giacomo Greco 🇮🇹💣