Hands down my favorite treatment of extensively drug-resistant organisms is nitrofurantoin.

From our winter issue: Matthew Phillips, MD, PhD, discusses the rise of these infections, the need to understand what we are witnessing, and find ways to combat them. #IDtwitter contagionlive.com/view/the-chang…

Based on this figure it looks like I should be prescribing Toyota Corollas to my patients.

wtf (where is the fish?) rbf (resting bass face) lol (lot of ladybugs) lmao (letting my armadillos out) omg (oh my gar)

lol this simulation is a bit too absurd.

This watches like a horror movie where the protagonist is waking into a trap. I just kept yelling “stop… stop!…STOP!”

Two journals tried paying peer reviewers and found increased acceptance, earlier reports, and no change in quality. WHAT A SURPRISE!

We see no possible way this could go wrong

The mitochondria

Wow! If anyone ever doubts the power of crowd sourcing, look at the vaccine RCT table that has been built already, in under 24 h! Unbelievable work by Jake Scott, MD Dr. Abhay Dand, Alejandro Diaz and Dr. Ali Sebastian Meza Vazquez! bradspellberg.com/vaccine-rcts

when you take rifampin

LOL! Ok…. good luck with that…

🆕🌟Super interesting! IDSA guidance recommend against the use of CAZ for the treatment of S. maltophilia Ceftazidime retains in vivo efficacy against strains of Stenotrophomonas maltophilia for which traditional testing predicts resistance Brad Spellberg journals.asm.org/doi/10.1128/ms…

The results of this study call into question the accuracy of susceptibility testing for organisms containing MBLs when conducted in nutrient-rich media and reiterate the need for clinical validation of in vitro susceptibility testing results, particularly if such resuls

We already modify media for antibiotic susceptibility testing for certain antibiotics (ex dapto, cefiderocol) to get more actuate results. It stands to reason that certain antibiotic resistance mechanisms (like MBLs) may also require modifications in the media to be accurate.

How much evidence is needed to revise established clinical practices? and, can data alone truly catalyze such shifts? Our 🆕🔥 Article Clinical Infectious Diseases super 🌟s McPhillips MD & Brad Spellberg Others Practicing With Intent: How to Teach an Old Dogma New Tricks academic.oup.com/cid/article/do…

STAGGERING: This new study of 133 countries is the first to estimate the impact of all USAID’s work. In 2 decades, it saved *92M* lives. Current cuts, if not reversed, are forecast to cost *14M* lives thru 2030. thelancet.com/journals/lance…

Just. Wow. As we went over Mexico and the U.S. this morning, I caught this sprite. Sprites are TLEs or Transient Luminous Events, that happen above the clouds and are triggered by intense electrical activity in the thunderstorms below. We have a great view above the clouds, so

Full video of President Whitmore’s speech from Area 51 little more than a half hour ago:

COVID-19 really broke America. The Failure of Life Expectancy to Fully Rebound to Prepandemic Levels jamanetwork.com/journals/jama/…