Very grateful to this team for their support, hard work and dedication to make our lab a happy, friendly and awesome place. And we also don’t suck at the science. I just got promoted to W2 tenure track professor! 🎉 Thank you. Rheinische Friedrich-Wilhelms-Universität Bonn Uniklinik Bonn ImmunoSensation

Very grateful for the support from Pew Health for this project and Travis Lantz who is an amazing graduate student who is taking the lead on getting this project off the ground!

Our latest work is out in nature today! Using smFRET, we directly visualized recruitment of the eIF4F complex to the 5' cap of eukaryotic mRNAs and formation of an activated mRNA. Our findings reveal new and surprising roles for each eIF4F component. 1/3 nature.com/articles/s4158…

Amazing and inspiring story on RNA binding proteins and translation specificity! Congrats to all!

Ribosomal expansion microscopy reveals a subcellular map of translational machinery composition and regulation at the single-molecule level science.org/doi/10.1126/sc… Science Magazine Barna Lab

Very proud of my graduate students ⁦Adele Xu⁩ and Zijian Zhang & key members of our lab and collaborators ⁦⁦Garry P. Nolan⁩ & Sharon Pitteri lfor the incredibly hard work to characterize subcellular ribosomes. science.org/doi/10.1126/sc…

Great tools and tips for the field to study IRES-dependent translation. Beautiful dissection of true HOX IRES translation in developing embryos. Congrats to all Barna Lab Kathrin Leppek!

An important resource for the field! Excited to use these new tools to study a critical, yet under-appreciated mechanism of translational specificity. Congrats Barna Lab Kathrin Leppek!

A much needed set of tools and standards to study cellular IRES. So happy that this study was done. I especially like the smFISH that shows tissue specific expression of isoforms.

Happy to share our new work with Hao Nguyen on targeting mRNA translation of oncogenes by RNA structure remodeling with a small molecule zotatifin. Congrats to ⁦Duygu Kuzuoglu Ozturk⁩ an amazing postdoc and all the authors and collaborators! cell.com/cancer-cell/fu…

Thanks Levi Gadye and Laura Kurtzman for the thoughtful and creative press release! UC San Francisco UCSF Helen Diller Family Comprehensive Cancer Ctr

We are grateful to the Rivkin Center for supporting our efforts to develop new types of engineered NK cells for ovarian cancer treatment. rivkin.org/blog/livnat-je… #CellTherapies, #RivkinCenter,#Immunotherapy, Ovarian Cancer Research Alliance

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Belated post! If you haven’t seen our recent work science.org/doi/10.1126/sc… , here’s a 🧵 highlighting the two techniques we developed to study subcellular populations of mammalian ribosomes and some cool findings these tools helped us uncover: (1/18)

New protocol drop! 🧪 Check out our polysome profiling in primary differentiating murine adipocytes 🐭🧫 — a step-by-step guide to studying translational control during adipogenesis. 👉 star-protocols.cell.com/protocols/4182 Claudio Villanueva Ph.D.

Small-molecule RNA therapeutics to target prostate cancer dlvr.it/TKlCgV

Excited to share our recent work, which addressed a mechanism by which the eukaryotic ribosomes increase the fidelity of mRNA translation than prokaryotic ribosomes through the eukaryote-specific tentacle-like ribosome structure. academic.oup.com/nar/article/53…

Excited that our nucleolus mapping paper just came out today in Nature! Truly an amazing study from even more amazing due of Sofi Quinodoz & Lifei jiang w/ Denis LJ Lafontaine & Sebastian Klinge and other fantastic co-authors nature.com/articles/s4158…