It's online now! Allosteric Regulation of Oligomerization by a B12 Trafficking G-Protein Is Corrupted in Methylmalonic Aciduria cell.com/cell-chemical-…

My first Science paper! 😀 My favorite buddies vitamin B12 and radicals Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair science.sciencemag.org/content/366/64…

The #immune system mimics a #pathogen! How #itaconate is used to derail a #radical #B12 #metalloenzyme - just out in #Science and the accompanying perspective by Amy Boal! The immune system mimics a pathogen science.sciencemag.org/content/366/64…

Mobile loop dynamics in adenosyltransferase control binding and reactivity of coenzyme B12 pnas.org/content/early/…

B12 enzymes are more flexible than one might think. (or how to challange a crystallographer) Now on bioarchive.@XtalRom @harshagowda10 #cobalamin #B12 Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B12 delivery and repair biorxiv.org/content/10.110…