🎉Another PhD defence at @IIMCB! Agnieszka Czarnocka-Cieciura (Laboratory of RNA Biology – ERA Chairs) defended her thesis “"The utilization of advanced RNA sequencing technologies to investigate post-transcriptional mechanisms involved in the regulation of gene expression” 🧬 💐

❄️NEW PRE-PRINT❄️Happy to see our latest work online. Here we present a simple solution to the preferred orientation problem in cryo-EM: the use of ultrasonic excitation during vitrification! Details in the 🧵 below... #cryoEM #structuralbiology [biorxiv.org/content/10.110…]

Behold! Our new paper in RNA Journal is finally here. This was a highly collaborative work with loads of nanopore data, poly(A) measurements and unexpected results sheding new light on mRNA 3'end processing in brain. Enjoy! rnajournal.cshlp.org/content/early/…

I'm excited to share that our latest review, “Mapping rRNA, tRNA, and mRNA Modifications in Ribosomes at High Resolution”, has just been published in Trends in Biochemical Sciences! Read the full review here 👉sciencedirect.com/science/articl…

Hi folks. My software for non-adenosine detection in ONT DRS data is now compatible with pod5 format/Dorado output. Check it out! #ninetails #iimcb #lrb #oxford_nanopore #nanopore github.com/LRB-IIMCB/nine…

I am happy to share our work on the mechanism of prokaryotic immunity by a reverse transcriptase associated with an SMC-family ATPase, now published in Nature Communications! 🔗 nature.com/articles/s4146… (🧵 on the bioRxiv version ⬇️)

Drodzy, by tradycji stało się zadość, naukowcy przygotowali petycję vs 2025 ws finansowania nauki, zwłaszcza Narodowe Centrum Nauki Nauka i badania, w kraju, który jest 20-tą gospodarką świata, powinny być priorytetem ponad podziałami. Apelujemy do wszystkich, którzy rozumieją potrzebę

Today in nature , we highlight how a cousin of CRISPR-Cas10, mCpol, establishes an evolutionary trap in anti-phage immune systems. Check out Erin Doherty's and my work from Doudna lab here: nature.com/articles/s4158…

🚨 Postdoc Opportunity in Kraków! Join the Jagiellonian University’s MCB to explore structural biology, biochemistry & drug design in our OPUS 24 project on the hypusination pathway. 🧬 Deadline: Oct 16, 2025 📅 Start: Q1 2026 👉 Details: mcb.uj.edu.pl/en_GB/oferty-p…

The Peters lab is looking for a new team member! The role transposons play in evolution, basic mechanisms regulating transposition, and applying transposons as tools for genome modification with a special focus on guide RNA-directed transposition cornell.wd1.myworkdayjobs.com/CornellCareerP…

HIRING! STOP lab is looking for a Research Assistant (Technician) with experience in protein expression and purification Center for Advanced Technologies IMBB AMU Poznań UAM Poznań. Job & project description and how to apply here: euraxess.ec.europa.eu/jobs/367610

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has

If you're curious about how cells quickly eliminate misfolded proteins produced under proteotoxic stress or during cell cycle progression, check out our latest article in Nature Communications doi.org/10.1038/s41467…

1/ 🚨 New preprint out! Using high-resolution mapping of active(!) RNPIII in human cells, we reveal that transcription termination—not initiation—is the bottleneck in RNAPIII kinetics on tRNA genes. biorxiv.org/content/10.110… 🧵

Very interesting! I'm routinely using described here 'decoy classification' strategy (i.e. I'm avoiding 2D class) and sometimes it gives amazing results, but for some difficult targets a really good 3D reference is required. I'm curious to see it in an automated workflow!

📢Paper alert📢our collaborative work led by Dr Roy IIT Hyderabad got published in Nucleic Acids Research. A DNA end-binder (DEB) that selectively binds to DNA termini and inhibits DNA repair, ideal for targeting DNA breaks Congrats Saanya Yadav et al doi.org/10.1093/nar/gk…

Friday Flower 008: Tulip 🌷 Tulip’s pastel colors and waxy cuticle that scatters light give them a soft watercolor look. The “broken” petals of Semper Augustus, created by a virus, became some of the most famous and valuable flowers in history... and their genome is 34Gb 🤯

🚀 Postdoc opening! Join our Structural Biology Lab at IFB UG & MUG to work on an FENG-funded (FNP FIRST TEAM) project advancing new DNA amplification strategies 🔬 Learn more & apply 👇 en.biotech.ug.edu.pl/news/114229/of… #postdocjob #postdoc Gdański Uniwersytet Medyczny (GUMed) Uniwersytet Gdański

📢 Open Recruitment: Postdoctoral Researcher at IMol! We have exciting news! The group of Dr. Piotr Gerlach at IMol is looking to hire a Postdoctoral Researcher! 🔗 Full Details and Application: euraxess.ec.europa.eu/jobs/383055 #hiring #postdoc #IMol #NCN #sonatabis

OpenFold3-preview (OF3p) is out: a sneak peek of our AF3-based structure prediction model. Our aim for OF3 is full AF3-parity for every modality. We now believe we have a clear path towards this goal and are releasing OF3p to enable building in the OF3 ecosystem. More👇