C-Trap publication on RNase H1 bidirectional exoribonuclease activity! 🧬🥳Congratulations to Bo Sun's lab and Wei Li's lab! nature.com/articles/s4146…

Cryo-EM is a bit of an imaging miracle. We collect 2D images with stupid amounts of noise. We don’t know what we’re looking at, or from which way. Yet some how we can churn it over and get to see (actually see) how life works on molecular scales in 3D. How?

Preprint just dropped!🎙️We discover molecular mechanisms of the excruciatingly painful sting of the Scarlet Velvet Ant (Dasymutilla occidentalis). Title: "Multiple mechanisms of action of an extremely painful venom." 🧵 1/N biorxiv.org/content/10.110…

Hey #teamtomo!Our 1st❄️🔬work Human Technopole is finally out!🥳nature.com/articles/s4159… Serialized On-grid Lift-In Sectioning for Tomography(SOLIST) enables a biopsy at the nanoscale and high-res❄️STA from🧍‍♀️organoids and🐭liver, brain and heart tissue!Thread by Gaia Perone below!

crefDenoiser IUCrJ doi.org/10.1107/S20522… ETH Zurich Politechnika Wrocławska Harvard Medical School HMS_SysBio Swiss National Science Foundation Novartis #3Dreconstruction #imageprocessing #computationalmodeling #cryoEM; #denoising #neuralnetwork IUCr #openaccess

New Title Alert: AreTomo3- a multi-GPU accelerated software package that enables real-time fully automated reconstruction of cryoET tomograms in parallel with cryoET data collection. More here: buff.ly/46ybnGi #SBGrid #structuralbiology #SBGridsoftware

🧵1/5 I'm so proud to share these incredible findings from our collaborative work with Amara Ali & Juan Reguera lab about Alphaviruses, particularly the chikungunya virus!! Highlights in the 🧵👇 nature.com/articles/s4146…

Happy to share, ARTEMIS is now published at Nucleic Acids Res! ARTEMIS is a tool for RNA/DNA 3D structure superposition and structure-based sequence alignment. It allowed us to identify an intriguing structural similarity between Lysine and M-box riboswitches! doi.org/10.1093/nar/gk…

Mesoscale Explorer molstar.org/me/ Paper out !! Excellent work with Alexander Rose David S. Goodsell 🏳️‍🌈  and David Sehnal doi.org/10.1002/pro.51…

Our in-situ structural analysis of the Ebola virus nucleocapsid is now published in Cell! Using cryo-FIB-ET, we revealed a 9Å structure, identifying novel layers and conserved interfaces that may serve as antiviral targets. #Ebola #Virology #StructuralBiology

🚀Announcing my first (co)first-author manuscript 🚀 "Cell attachment and tail contraction of S. aureus phage phi812" 🔗bit.ly/Phi812 Check out the 🧵 to explore the structural details of phage interaction with Gram+ bacteria🤯 #PhageTherapy #Research #PhDlife 1/11

"four freely available tools that can be used in fundamental crystallography courses for #bachelor's and #master's curricula focused on #symmetry handling and #visualization: #BCS, #CSD, #VESTA & #Jmol." 😀😀doi.org/10.1107/S16005… Journal of Applied Crystallography IUCr #crystallography #education

Hannah Mischo and I wrote a review on the importance of good endings. A pre-proof version is now published in Journal of Molecular Biology : Fateful decisions of where to cut the line: Pathology associated with aberrant 3’ end processing and transcription termination sciencedirect.com/science/articl…

I'm excited to share our latest review on #RNA structure prediction and modeling! 🧬 Dive into advances using both theoretical approaches and experimental data. Free access available until Nov 13, 2024!👇 👉 authors.elsevier.com/a/1jpyq3SNvcAc… #RNAstructure #StructuralBiology #Modeling

Our paper out today @nature: phages reconstitute NAD+ to counter bacterial immunity Phaged invented a new biochemical pathway for NAD+ synthesis - including previously unknown enzymatic reactions - to evade bacterial defenses Congrats Ilya Osterman! nature.com/articles/s4158…

In this paper, we answer a ~70-year-old question: How does the bacterial flagellum assembles, several micrometers away from the cell surface?

Jeśli nie jest Ci obojętny los Narodowe Centrum Nauki podpisz petycję o zwiększenie finansowania nauki w 2025. Studenci, akademicy, przedsiębiorcy Polska Akademia Nauk KRASP Dariusz Jemielniak A. Gmiterek-Zabłocka petycjeonline.com/list_otwarty_d…

Hey, I am looking for a PhD student interested in smart cell delivery, protein engineering, synthetic and structural biology. details can be found here: 👉 lnkd.in/d2zF95Na Uniwersytet Jagielloński Synchrotron SOLARIS Malopolska Centre of Biotechnology UJ

Happy to share our latest work from the Liz Kellogg ❄️🔬 lab, in collaboration with the Protein Technologies Center at St. Jude, where we describe the structure of Fanzor2. Special thanks to my co-authors, Zuhaib Qayyum and Ajay Tanwar. nature.com/articles/s4159…

Our review article “Recent advances in expression screening and sample evaluation for structural studies of membrane proteins” is out in Journal of Molecular Biology. We discussed the recent advances and new applications of FSEC. Congrats to Huang and Zhang! #OpenAccess sciencedirect.com/science/articl…