The central dogma of molecular biology states that genetic information flows from DNA and RNA to protein, with reverse transcription converting RNA to DNA. In the pursuit of understanding how bacteria defend themselves from viral infection, two groups have found alternative

Doing good science is 90% finding a science buddy to constantly talk to about the project.

BREAKING NEWS The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

EMBL congratulates Victor Ambros and Gary Ruvkun on winning the 2024 #NobelPrize in Physiology or Medicine for the discovery of microRNA and its role in post-transcriptional gene regulation.

Everybody's talking about the nobel prize, and it reminded me of my favorite Hopfield paper, Kinetic Proofreading! It's a blueprint for how life prevents information decay by spending extra energy. I wrote a blog post on it a few years ago devonstork.com/p/kinetic-proo…

We are deeply saddened by the passing of Ratan Tata, a visionary leader, philanthropist, and former President of IISc's Court. A condolence meeting was held today at the Institute to pay respects to him.

Timescales in Cell Biology

facebook.com/share/p/4HaMDZ… Ashwin 🇮🇳 Pls do spread the words… Govind is missing

📢 Our work on CDS #m6A mediated RNA decay (CMD) is out in Molecular Cell ! Decay relies on ribosome pausing at m6A containing codons. Great collab with the Zarnack lab & colleagues. Check it out here: authors.elsevier.com/sd/article/S10… Thank you IMB Mainz Universität Würzburg #UniWürzburg RMaP - TRR319 🥳

Hearty congratulations to Prof Raghavan Varadarajan on winning the 2024 Tata Transformation Prize🎉 His lab aims to develop a cost-effective vaccine for Respiratory Syncytial Virus (RSV) which affects 30 million people annually. iisc.ac.in/events/prof-ra…

Congratulations, Olivier Duss, Simone Köhler, and Eva Kowalinski! The three EMBL Group Leaders have received ERC Consolidator Grants for their innovative research projects aimed at understanding fundamental cellular mechanisms. Read more here 👉 embl.org/news/awards-ho…

Meet Romain Linares, cryo-electron microscopy (cryo-EM) expert at EMBL Grenoble. In this interview, he talks about his role in managing the cryo-EM platform to explore molecules at the atomic level and his passion for stargazing. embl.org/news/people-pe…

EMBL Group Leader Olivier Duss and his research team discovered how two molecular machines in bacteria work together and watched their interactions as a real-time movie. Read the full article to discover how they put snapshots in motion: embl.org/news/science-t…

Nature research paper: Tracking transcription–translation coupling in real time go.nature.com/3VLPiA7

First paper of our lab today nature by Nussi! We provide a real-time movie on how #transcription and #translation cooperate using multi-color #single-molecule FM: we find long-range #ribosome-#polymerase communication mediated by #RNA looping! EMBL doi.org/10.1038/s41586…

Online Now: Structural basis of 5′ splice site recognition by the minor spliceosome dlvr.it/THLDnx

Structural basis of 5′ splice site recognition by the minor spliceosome dlvr.it/THtryt

RNA-guided systems span kingdoms, from bacterial immunity to eukaryotic gene regulation. How did they evolve? We traced the origins of CRISPR-Cas13 and identified its likely ancestor: an RNA-based toxin-antitoxin (TA) system. Here’s what we uncovered: cell.com/cell/fulltext/… 1/8

Amazing work - CRISPR-Cas13 systems likely evolved from Type III TA systems!

50 years of structural biology in the French Alps! 🎂 EMBL Grenoble celebrates its anniversary alongside alumni, partners, and collaborators, reflecting on past and future achievements. Congratulations!