Miguel opened today's #biocat2024 session as the first invited speaker. He presented an exciting lecture on our lab's UPOs research. #TUHH #Hamburg

We're attending Jornadas Españolas de Biocatálisis #JEB2024 at San Sebastián!🌊 Paula Sanz is delivering today a speech about our latest research with UPOs. But also, come find Julia (P1-10) and Silvia (P1-7) at poster session!📰

Combining biocatalytic oxyfunctionalisation and organocatalytic aldol reaction to access chiral β-hydroxy ketones; Y. Wang, chiara domestici N. Teetz, D. Holtmann Miguel Alcalde Laboratory M. Wang, W. Qi, W. Zhang & F. Hollmann doi.org/10.1016/j.mcat…

Julia, Paula and Silvia last week at #JEB2024 SSebiot👩‍🔬

Last week the #JEB2024 were celebrated in San Sebastian. Many thanks to the organizing committee for selecting my abstract for an oral presentation. Also my colleagues Silvia and Julia Murciano brought their respective posters. Great time to meet people a talk about science!!!

Some memories from #Biocat2024 ✨

2024 #NobelPrize laureate in chemistry David Baker has succeeded with the almost impossible feat of building entirely new kinds of proteins. In recent years, one incredible protein creation after the other has emerged from Baker’s laboratory. They range from new nanomaterials

This year’s chemistry laureates Demis Hassabis and John Jumper have developed an AI model, AlphaFold2, to solve a 50-year-old problem: predicting proteins’ complex structures. Check out two examples of protein structures determined using AlphaFold2. First up, a bacterial enzyme

Last Friday we attended the 2nd PosterCat! PhD students from the group did an awesome job sharing their thesis projects with flash presentations. Great initiative from Instituto de Catálisis y Petroleoquímica (CSIC) ! Looking forward to next year's PosterCat! Here you can spot the presenters from the lab 👨‍🔬👩‍🔬

We're delighted to share that we've host the first in-person BLADE2CIRC consortium meeting at Instituto de Catálisis y Petroleoquímica (CSIC) ! We discussed our latest results, explored future approaches, and enjoyed a tour of downtown Madrid, which concluded with a lovely dinner near the Royal Palace.

Our first face-to-face consortium meeting happened in Madrid last week! 🇪🇸 What a great discussion, lab visits, & city exploration that CSIC & EvoEnzyme organized for the rest of the partners. So excited for what's next! #research #collaboration #science #BLADE2CIRC

Un grupo de estudiantes del Máster de Biotecnología de la UAM Autónoma Madrid nos visitó ayer en el Instituto de Catálisis y Petroleoquímica (CSIC) Les preparamos un taller biocatalítico con varias rotaciones, en colaboración con Miguel Alcalde Laboratory Estupendos alumnos que esperamos disfrutaran de las #enzimas Postgrado CSIC Delegación Institucional del CSIC en Madrid

Yesterday we had the pleasure of hosting Dr. Huimin Zhao at Instituto de Catálisis y Petroleoquímica (CSIC). He gave an inspiring talk on synthetic biology, machine learning, and lab automation, leading to a stimulating discussion on how AI-driven algorithms are shaping our field and what lies ahead Huimin Zhao

Many thanks to Prof. Alice Ting for visiting Instituto de Catálisis y Petroleoquímica (CSIC) and sharing her insightful work in a seminar titled: "Engineering proteins to map and manipulate molecular and cellular networks". A privilege to host her, truly inspiring!

Magnífico seminario de Alice Ting Alice Ting, investigadora de Stanford University Nos ha hablado de tecnologías para estudiar ensamblajes moleculares y celulares con alta resolución espacial en cultivos vivos y organismos. Un privilegio para nuestro instituto contar con su presencia

Amplia representación de nuestro instituto en la segunda jornada del Congreso #SECAT2025 en Alcalá de Henares Comunicaciones orales, charlas flash, pósteres y dos charlas magistrales (keynotes) a cargo de María Asunción Molina (Premio Tesis Sociedad Española de Catálisis 2023) y Miguel Alcalde

One more year, we're attending #Biotrans2025! You can spot our PhD students, Julia Murciano and Yahan Wu, at the poster session: ▪️Julia Murciano: poster P287 ▪️Yahan Wu: poster P371 Looking forward to engaging discussions and inspiring science in Basel!

See you next time, Basel! 👋 Julia and Yahan had a great time at #BIOTRANS2025 , and it was a pleasure to share the experience with Ivan and Mikel from EvoEnzyme as well. Looking forward to the next edition and more outstanding science! 🧬

Big moments at the Protein Engineering GRC!🧬 This week at Bryant University (USA), our PI Miguel Alcalde gave a talk titled “When Directed Evolution Met Ancestral Enzyme Resurrection” and caught up with old friends from Frances Arnold’s lab at Caltech #GRC2025 Gordon Research Conferences

My penultimate PhD project is out in Nature Chemical Biology! We engineered LaccID, a cell surface-specific enzyme for proximity labeling and EM. Derived from an ancestral laccase, it performs the same chemistry as APEX2 but using O2 instead of H2O2. nature.com/articles/s4158…