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.University of Glasgow scientists at the @CRUK_SIb have made an unusual discovery that could help to identify patients who are up to two and a half times more likely to respond to currently available cancer drugs 🔬🧬 Read more ➡️ gla.ac/42xN3m9

And now the final version Nature Cancer! 🥳 rdcu.be/dxcnr Some updates... 1/6 tldr; mtDNA mutations, found in ~50% of all cancers, are immunomodulatory - we can mimic the effect to make non-mtDNA mutant cancer sensitive to immunotherapy drugs.

There comes a time in a PIs life where they rip free of the chains that bind them, and simply say all the things they want to say about a great paper. So here we go, a new paper driven by Mahnoor M and led by Payam A. Gammage and I: nature.com/articles/s4301… Prepare to be annoyed

A bonus perk to publishing your first paper that I hadn’t been aware of is being woken up to surprise flowers by your biggest supporters🥰 Marco De Donatis Dr Amy Shergold (she/her)

And the moment you've all been waiting for... Our top downloaded article in 2023: Mechanisms driving the immunoregulatory function of cancer cells by Antoinette van Weverwijk & Karin de Visser go.nature.com/3HoMqBk Cancer at Nature Portfolio The Netherlands Cancer Institute Oncode Institute #NRCtop10of2023 pic.x.com/xA6sUzOkYj

Finally, I had the time to read this excellent comment from Martin Picard & colleagues nature.com/articles/s4225… This concept of hypermetabolism in mitochondrial disorders could be applied to cancer

Scientists at CRUK Scotland Inst have found that certain mutations in cancer cells make them much more likely to respond to immunotherapy treatment. With our funding, they're now working on a plan to mimic these changes and make immunotherapy effective against more cancers 👇

A piece from Nature Cancer giving an overview on our paper investigating the role of recurrent mtDNA mutations in cancer for those who haven’t had the chance to read the whole paper yet!👌🏽 nature.com/articles/s4301…

Very happy to share my thoughts about the importance of allyship with Science and Innovation at Cancer Research UK. Thanks to everyone involved in our EDI CRUK Scotland Inst who helped me shape my thoughts! news.cancerresearchuk.org/2024/05/15/the…

And that’s a wrap on #EACR2024! I had a wonderful time listening to all the amazing science happening as well as meet some lovely scientists. Little old me also got to present my PhD work through a proffered paper talk which was an incredibly valuable experience!

New analysis from the The Royal Society shows just how high UK visa costs for researchers are compared to upfront costs for similar visa routes in 13 other countries. Here, we take a look at how the UK compares to countries in the G7 included in the analysis 🔍⤵️ 1/5

Had the loveliest few days celebrating becoming Dr. Mahmood!🎓 and how lucky to be able to do it surrounded by my Glasgow family who have helped me grow into a scientist and person that Mahnoor from 5 years ago would have been proud to be!

So much about the immigration and asylum system is just completely unknown to people day to day. Some examples:

🚨PhD position available with Matt Dalby and myself, bioengineering the bone marrow microenvironment and more! Please contact me to enquire and share with any keen bioengineers 🦴🩸