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Clinical sensitivity and specificity of a high-throughput microfluidic nano-immunoassay combined with capillary blood microsampling for the identification of anti-SARS-CoV-2 Spike IgG serostatus. dx.plos.org/10.1371/journa…

Simone's paper: "Nature-Inspired Circular-Economy Recycling for Proteins: Proof of Concept." was one of the most downloaded papers in 2021 at Advanced Materials. Simone Giaveri Francesco Stellacci EPFL School of Engineering #AdvancedMaterials #PURE #cellfree #synbio onlinelibrary.wiley.com/doi/10.1002/ad…

"Imagine the kind of technological progress humanity could make if we could start designing novel proteins for personalised medicines, industrial applications like new enzymes, or better, more sustainable materials." forbes.com/sites/davidpro…

A #SynCell2023 talk about useful things we can do with cell-free systems by Sebastian Maerkl of the Maerkl Lab: cheaper PURE systems, chemoststs and other useful #bioengineering tricks. BaSyC #synbio

"A field-capable rapid plant DNA extraction protocol using microneedle patches for botanical surveying and monitoring" We published our first article with the master and bachelor student MAKE project Genorobotics! Congrats everybody who contributed! bsapubs.onlinelibrary.wiley.com/doi/10.1002/ap…

C2CAplus: a one-pot isothermal circle-to-circle DNA amplification system. Laura and Paula's work on developing an improved phi29 based DNA amplification system is out now on BioRxiv! biorxiv.org/content/10.110…

I wrote a short discussion "On biochemical constructors and synthetic cells", which was just published. Check it out: royalsocietypublishing.org/doi/10.1098/rs…

Laura and Paula's paper is out now! "C2CAplus: A One-Pot Isothermal Circle-to-Circle DNA Amplification System" pubs.acs.org/doi/10.1021/ac…

Congratulations to our post-doc Fanjun who was just awarded a SNF Spark grant! Spark grants fund "rapid testing or development of novel and unconventional scientific approaches, methods, theories, standards and ideas", which is right up our alley! snf.ch/en/8EWqXT6CZ7w…

Our cellbase.epfl.ch is back up and running! This database contains over 7000 single-cell movies of strains in the yeast-GFP library grown on a microfluidic chemostat under various environmental conditions: pnas.org/doi/abs/10.107…

Ragu's paper describing a minimal PURE system is now on BioRxiv!! Towards self-regeneration: exploring the limits of protein synthesis in the PURE cell-free transcription -translation system biorxiv.org/content/10.110…

Targeting protein-ligand neosurfaces using a generalizable deep learning approach biorxiv.org/content/10.110…

Amogh's comprehensive review of microfluidic approaches and applications in cell-free synthetic biology is out now! #microfluidics #cellfreesynbio #synbio #syntheticbiology frontiersin.org/articles/10.33…

Laura's paper from the Stellacci lab (Francesco Stellacci) is out now: Nature-Inspired Recycling of a Protein Mixture into a Green Fluorescent Protein-based hydrogel - now published in RSC Sustainability pubs.rsc.org/en/content/art…

Ragu's paper is now officially out in ACS SynBio: Towards Self-regeneration: Exploring the Limits of Protein Synthesis in the Protein Synthesis Using Recombinant Elements (PURE) Cell-free Transcription–Translation System | ACS Synthetic Biology pubs.acs.org/doi/10.1021/ac…

The Maerkl Lab is hiring one or two graduate students to work in the area of cell-free synthetic biology, specifically synthetic cell engineering! Deadline for our EDBB doctoral program is Nov 1st ... See below for more information: eth-gethired.ch/de/jobs/detail…

Laura (SuNMIL) and Laura's paper on running the PURE system for weeks using a simple mesoscale dialysis system is now on bioRxiv!! "Long-term protein synthesis with PURE in a mesoscale dialysis system" biorxiv.org/content/10.110…

Pao-Wan's review on cell-free regulatory components is out now! Regulatory Components for Bacterial Cell-Free Systems Engineering | ACS Synthetic Biology pubs.acs.org/doi/10.1021/ac…

Laura and Laura's paper is out now in ACS Synthetic Biology. "Long-Term Protein Synthesis with PURE in a Mesoscale Dialysis System" pubs.acs.org/doi/full/10.10…

Fanjun and Amogh's paper is out now on BioRxiv: "Continuous in situ synthesis of a complete set of tRNAs sustains steady-state translation in a recombinant cell-free system." biorxiv.org/content/10.110…