HIV + COVID ! "Rapid Emergence and Evolution of SARS-CoV-2 Variants in Advanced HIV Infection" biorxiv.org/content/10.110… "Our findings show remarkable intra-host genetic diversity of SARS-CoV-2 in advanced HIV infection ...

Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants. Preprint from Zunlong Ke in collaboration with Tom Peacock wendybarclay Abhay Kotecha Tristan Croll and others. biorxiv.org/content/10.110…

Hi everyone! I am going to be running my first half marathon in May for the amazing abdulsomedsadat on hackerone here. Please check out my fundraising page - I am hoping to upload updates here if anyone wants to keep up to date with my training progress! Thanks😊 ajbellgreatbristolrun2024.enthuse.com/pf/maddy-newby

KEY STUDY : SARS-COV-2 and HIV, Contrary Viral Strategies in Similar Disguise (published June 2021) mdpi.com/2076-2607/9/7/… Figure 1 Comparison of HIV-1 and SARS-CoV-2 key viral features

While glycans are essential for antibody effector functions, it seems that Fc glycosylation is not required for IgG-B-cell receptor function... nature.com/articles/s4146…

A very recent NEJM paper reviewed the use of focused ultrasound to the brain in 3 patients with Alzheimer's disease nejm.org/doi/full/10.10… Now this is the focus of a 60 Minutes segment

Our paper on " SARS-CoV-2 Omicron XBB lineage spike structures, conformations, antigenicity, and receptor recognition" is now bioRxiv biorxiv.org/content/10.110…

HIV-1 vaccination induces CD4-binding site (CD4bs) neutralizing antibodies (nAbs). sciencedirect.com/science/articl… Bhishem thakur Victoria Stalls Kartik Manne Megan Kopp @RoryCHenderson Duke Center for HIV Structural Biology DHVI Structural Biology Duke Human Vaccine Institute

Excited to share the release of our pre-print unveiling the design of de novo single-domain #antibodies with atomic-level precision, as revealed by #CryoEM! UW Biochemistry Institute for Protein Design Work co-led by Joseph Watson Nate Bennett @RobertRagotte biorxiv.org/content/10.110…

The IgG-specific endoglycosidases EndoS and EndoS2 are distinguished by conformation and antibody recognition Journal of Biological Chemistry Max Crispin Biological Sciences #glycotime doi.org/10.1016/j.jbc.…

Happy to share a link to the final published version of our paper on the structural basis of bacterial IgG deglycosylation by EndoS2. Kudos to @mattiascollin for finding this fascinating enzyme. #glycotime doi.org/10.1016/j.jbc.…

🎉 Happy 98th Birthday Sir David Attenborough! 🎉 It was an honour to welcome you to our μ-VIS X-ray Imaging Centre facility during the filming of Attenborough and the Giant Sea Monster last year. Keep inspiring us all! 🌍

Check out this study cell.com/cell-host-micr… Victoria Stalls determined cryo-EM structures to visualize the epitopes of the vaccine-elicited antibodies and define the structural basis of their neutralization breadth.

Four new studies inform on the multistep path to generate broadly active HIV-1 antibodies Science Magazine commentary on 4 studies out today in Science Science Immunology & Science Translational Medicine

I'm so proud to have completed yesterday's Bristol half marathon for @againstbc! Never thought I'd be capable of anything like this, so thank you to everyone who supported me and donated! ajbellgreatbristolrun2024.enthuse.com/pf/maddy-newby…

Interesting study Callum Ives @ElisaTelisa shows how important is N-glycosylation at N343 for receptor binding domain of SARS-CoV-2 tinyurl.com/323m9e85 #glycotime

HIV-1 neutralizing antibodies in SHIV-infected macaques recapitulate structurally divergent modes of human V2 apex recognition with a single D gene biorxiv.org/content/10.110…

Excited to share my first paper has been published in Nature Methods!! A big thanks to my amazing co-authors Callum Ives and of course to the support of my team and my supervisor @ElisaTelisa 🎉🎉🎉🔺🟢🟦

New Nature Methods #glycotime! Restoring protein glycosylation with GlycoShape (glycoshape.org) ihttps://www.nature.com/articles/s41592-024-02464-7 @ElisaTelisa University of Southampton