Lefteris Zormpas (@lzormpas) 's Twitter Profile
Lefteris Zormpas

@lzormpas

PhD candidate, researcher, citizen - reading, thinking, creating.
๐Ÿ‡ฌ๐Ÿ‡ท

ID: 1532753935299125250

calendar_today03-06-2022 16:01:09

60 Tweet

29 Followers

268 Following

Lefteris Zormpas (@lzormpas) 's Twitter Profile Photo

The amount of papers being published every week in spatial trascriptomics is disproportionate to the amount I can read in a week... However, one can find real gems in "lower level" journals. You just have to find the time to really dig through the pile of publications...

Hao Yin (@haoyin20) 's Twitter Profile Photo

SpaRx Predict (Spatial) drug responses of tumors using single-cell-resolved #SpatialTranscriptomics #CosMx Lung cancer #MERSCOPE Trained on GDSC CCLE cell line (>1k) drug screening database Graph-based Adversarial adaptation @BriefingBioinfo 2023 academic.oup.com/bib/article/24โ€ฆ

SpaRx

Predict (Spatial) drug responses of tumors using single-cell-resolved #SpatialTranscriptomics #CosMx Lung cancer #MERSCOPE

Trained on GDSC CCLE cell line (>1k) drug screening database

Graph-based Adversarial adaptation

@BriefingBioinfo 2023
academic.oup.com/bib/article/24โ€ฆ
NimwegenLab (@nimwegenlab) 's Twitter Profile Photo

I see we are getting to the stage of the discussion where people are starting to defend UMAP saying it can 'reveal patterns' or 'structure' in the data. Without ever specifying what precisely these patterns/structures represent. This is not surprising because hardly anybody 1/n

Hao Yin (@haoyin20) 's Twitter Profile Photo

Molecular & Spatial Signatures of๐ŸญEmbryonic Endothelial Cells at Single-Cell Resolution e9.5/12.5/15.5 #ArterioVenousHierarchy & #Organotypicity of Embryonic #EndothelialCell scRNAseq #MERFISH #SpatialTranscriptomics #SciArt William Pu lab Circulation Research 2024

Molecular & Spatial Signatures of๐ŸญEmbryonic Endothelial Cells at Single-Cell Resolution
e9.5/12.5/15.5

#ArterioVenousHierarchy & #Organotypicity of Embryonic #EndothelialCell

scRNAseq
#MERFISH #SpatialTranscriptomics
#SciArt

William Pu lab <a href="/CircRes/">Circulation Research</a> 2024
Hao Yin (@haoyin20) 's Twitter Profile Photo

TransformerST #SpatialTranscriptomics Vision transformer Adaptive graph transformer Cross-scale internal graph network Image-gene co-representation: Gene expression+Spatial coordinates+Histologic images "could achieve super-resolved resolution of a single cell per subspot" w/o

TransformerST
#SpatialTranscriptomics

Vision transformer
Adaptive graph transformer
Cross-scale internal graph network

Image-gene co-representation:
Gene expression+Spatial coordinates+Histologic images

"could achieve super-resolved resolution of a single cell per subspot" w/o
Hao Yin (@haoyin20) 's Twitter Profile Photo

SpatialData spatialdata.scverse.org/en/latest/ Establish a global common coordinate framework-> Multi-modal #SpatialOmics integration Align multislice for 3D #SpatialOmics napari-spatialdata Work with (RNA) Visium Xenium CosMx MEFISH (protein) CycIF MIBI-TOF #ImagingMassCytometry +HE

SpatialData
spatialdata.scverse.org/en/latest/

Establish a global common coordinate framework-&gt;
Multi-modal #SpatialOmics integration
Align multislice for 3D #SpatialOmics

napari-spatialdata

Work with
(RNA) Visium Xenium CosMx MEFISH
(protein) CycIF MIBI-TOF #ImagingMassCytometry
+HE
Hao Yin (@haoyin20) 's Twitter Profile Photo

STCellbin Use Nuclei+Cell Membrane/Wall stains to improve #CellSegmentation & single-cell-resolved #SpatialTranscriptomics Tailored for #StereoSeq, but likely implementable for other ST methods Susanne Brix & Xun Xu labs GigaByteJournal 2024 gigabytejournal.com/articles/110

STCellbin

Use Nuclei+Cell Membrane/Wall stains to improve #CellSegmentation &amp; single-cell-resolved #SpatialTranscriptomics

Tailored for #StereoSeq, but likely implementable for other ST methods

Susanne Brix &amp; Xun Xu labs <a href="/GigaByteJournal/">GigaByteJournal</a> 2024
gigabytejournal.com/articles/110
Lefteris Zormpas (@lzormpas) 's Twitter Profile Photo

It is always great to share knowledge with fellow researchers and gather important feedback! Thank you for hosting me! #SpatialTranscriptomics

BGI Group (@thebgigroup) 's Twitter Profile Photo

#BGI-Research's cutting-edge liver studies have been selected as the cover story for Nature Genetics . These two studies integrate scRNA-seq and Stereo-seq data to characterize molecular signatures and interactions of liver cell types across different states including homeostasis,

#BGI-Research's cutting-edge liver studies have been selected as the cover story for <a href="/NatureGenet/">Nature Genetics</a> . These two studies integrate scRNA-seq and Stereo-seq data to characterize molecular signatures and interactions of liver cell types across different states including homeostasis,
Hao Yin (@haoyin20) 's Twitter Profile Photo

gganatogram: An R package for modular visualisation of anatograms and tissues based on ggplot2 Draw Animal/Plant organs or some cell organelles in R github.com/jespermaag/ggaโ€ฆ Jesper Maag F1000Research 2018 f1000research.com/articles/7-157โ€ฆ

gganatogram: An R package for modular visualisation of anatograms and tissues based on ggplot2

Draw Animal/Plant organs or some cell organelles in R

github.com/jespermaag/ggaโ€ฆ

<a href="/JesperMaag/">Jesper Maag</a> <a href="/F1000Research/">F1000Research</a> 2018
f1000research.com/articles/7-157โ€ฆ
Olympiacos FC (@olympiacosfc) 's Twitter Profile Photo

WE ARE THE @europacnfleague WINNERS! WE ARE THE CHAMPIONS! ๐Ÿ”ดโšช๐Ÿ†๐Ÿ‡ฌ๐Ÿ‡ท #Olympiacos #UECL #Champion #Winners #Europe #Greece #WeKeepOnDreaming

WE ARE THE @europacnfleague WINNERS! WE ARE THE CHAMPIONS! ๐Ÿ”ดโšช๐Ÿ†๐Ÿ‡ฌ๐Ÿ‡ท

#Olympiacos #UECL #Champion #Winners #Europe #Greece #WeKeepOnDreaming
Hao Yin (@haoyin20) 's Twitter Profile Photo

What is a cell type and how to define it? #DevoEvo Linking morphologic, geographic & functional attributes with Transcriptomic/Epigenomic taxonomy Connectomics Path-seq Retro-seq ...... How many neuron omic techniques have been/can be adapted for microvasculature?๐Ÿ˜†

What is a cell type and how to define it?
#DevoEvo

Linking morphologic, geographic &amp; functional attributes with Transcriptomic/Epigenomic taxonomy

Connectomics
Path-seq
Retro-seq
......

How many neuron omic techniques have been/can be adapted for microvasculature?๐Ÿ˜†
Ioannis Vlachos // @ioavlachos.bsky.social (@ioavlachos) 's Twitter Profile Photo

๐—ฆ๐—ง๐—”๐— ๐—ฃ: single cell (spatial?) Being asked what I think about it (NOT involved). 1) What is STAMP? Should I care about it? STAMP is a clever way of using ๐˜€๐—ฝ๐—ฎ๐˜๐—ถ๐—ฎ๐—น ๐—ฎ๐˜€๐˜€๐—ฎ๐˜†๐˜€ to get ๐—ถ๐—ป๐˜€๐—ฎ๐—ป๐—ฒ๐—น๐˜† ๐—น๐—ผ๐˜„ ๐—ฐ๐—ผ๐˜€๐˜ ๐˜€๐—ถ๐—ป๐—ด๐—น๐—ฒ ๐—ฐ๐—ฒ๐—น๐—น ๐—ฑ๐—ฎ๐˜๐—ฎ tinyurl.com/nwetc3te

๐—ฆ๐—ง๐—”๐— ๐—ฃ: single cell (spatial?)
Being asked what I think about it (NOT involved).
1) What is STAMP? Should I care about it?
STAMP is a clever way of using ๐˜€๐—ฝ๐—ฎ๐˜๐—ถ๐—ฎ๐—น ๐—ฎ๐˜€๐˜€๐—ฎ๐˜†๐˜€ to get ๐—ถ๐—ป๐˜€๐—ฎ๐—ป๐—ฒ๐—น๐˜† ๐—น๐—ผ๐˜„ ๐—ฐ๐—ผ๐˜€๐˜ ๐˜€๐—ถ๐—ป๐—ด๐—น๐—ฒ ๐—ฐ๐—ฒ๐—น๐—น ๐—ฑ๐—ฎ๐˜๐—ฎ
tinyurl.com/nwetc3te
Ioannis Vlachos // @ioavlachos.bsky.social (@ioavlachos) 's Twitter Profile Photo

**Please Retweet (Re-X?)** ๐Ÿ”ฅPostdoc #jobs in Spatial / Single Cell Omics Looking to become a #leader in #SpatialBiology? Love NGS & #MachineLearning? #Positions Harvard Medical School Broad Institute linkedin.com/jobs/view/4038โ€ฆ #hiring #lab #boston #research #aiml #biotech #Science