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It was a massive group effort with Omics PNNL @rmirmira @MirmiraLab lorenzopasquali Julia Laskin Lab Kristin Burnum-Johnson Dr. Carmella EvansMolina Science at PNNL Pacific Northwest National Laboratory Center for Diabetes and Metabolic Diseases Barbara Davis Center Purdue Chemistry

Delighted to share our publication on the critical role of #m6A as an adaptive safeguard mechanism in pancreatic β-cells during Type 1 Diabetes (T1D) onset. #DiabetesResearch Nature Cell Biology nature.com/articles/s4155… Here's a concise thread to highlight key findings:

Exited to share our new preprint characterizing murine ductal heterogeneity at single cell resolution coupled with organoid forming capacity and differentiation potentail of novel identified ductal populations. Stay tune for the follow up in human and in novel in vivo models. 👇

Great to reconnect with Jorge Ferrer, lorenzopasquali, and Meritxell Rovira during my visit to Centre for Genomic Regulation (CRG)! Huge thanks to Jorge for inviting me to present our lab's work IFIBYNE 🇦🇷 CONICET - UBA. Excited about starting new and thrilling collaborations!

Implications of noncoding regulatory functions in the development of insulinomas dlvr.it/T93m0G

Thrilled to share our latest publication @cellgenomics, exploring the activation of aberrant noncoding regulatory functions involved in the development of insulin-secreting neuroendocrine pancreatic tumors. cell.com/cell-genomics/…

Great work from Endocrine Regulatory Genomics Lab 👇👇👇

1/4 🧬 A study led by UPF and published in Cell Genomics reveals that #insulinomas, rare pancreatic beta cell #tumors, form due to epigenetic changes causing overexpression of oncogenes and insulin-related genes. Learn more: 👉🏾 tuit.cat/c6wZZ

We open a PhD position in our lab UPF Medicine and Life Sciences , if you like exploring never studied #fungi, understanding #biophysical principles that rule the limits of life, you like fancy #microscopy...then apply, we are looking for you! (RT appreciated:-) upf.edu/documents/2869…

Implications of noncoding regulatory functions in the development of insulinomas dlvr.it/TBvq6L

Thanks for highlighting our work now out Cell Genomics

We are hiring! Looking for a computational and an experimental #predoc to work on an exciting regulatory genomics project. Enthusiastic multidisciplinary team, amazing environment Biomedicina BCN UPF Medicine and Life Sciences endoregulatorygenomics.org/positions/

Finally out the printed version of our single cell atlas of the entire murine ductal tree gastrojournal.org/article/S0016-… Followed by a really nice editorial from Rohit Chandwani gastrojournal.org/article/S0016-… Thanks to all the collaborators Jennifer Bailey-Lundberg lorenzopasquali Miltenyi Biotec

🔥Hot paper from new investigators unmasks potential roles of specific ductal populations in pancreas regeneration and exocrine pathogenesis 🔗 ow.ly/z0Nt50TFCBL 🖋️ Meritxell Rovira Rovira_lab Jennifer Bailey-Lundberg Endocrine Regulatory Genomics Lab

📣 Next week HMar Research Institute & @upfbiomed #ScientificSeminar are back! 🗣️ Mario Cáceres (Mario Caceres - HMar Research Institute) and Lorenzo Pasquali (Endocrine Regulatory Genomics Lab - UPF Barcelona) will be the speakers of this second session of double seminars. 📆 Oct 24 ⏰12 h 📌Charles Darwin Room

Looking to set up your own lab? Or already have an established lab and open to move? Diabetes is one of the research priorities of UoB!! Please get in touch if interested! Diabetes UK Research

Job alert: Interested in pancreatic beta cells, a dash of genomics and novel treatment options for diabetes? We are looking for a post-doc!! Contact us for an informal chat! edzz.fa.em3.oraclecloud.com/hcmUI/Candidat…

En la diabetes de tipo 1, una enfermedad crónica autoinmune, las células beta del páncreas productoras de insulina son destruidas, lo que da lugar a graves complicaciones. 🛡️ Con el apoyo de #CaixaResearch, lorenzopasquali busca sentar las bases para crear células beta

lorenzopasquali Esta investigación cuenta con el apoyo de #CaixaResearch y es llevada a cabo por un consorcio formado por: 👉Endocrine Regulatory Genomics Lab, de UPF Barcelona 👉Heiko Lickert, de Helmholtz Munich | @HelmholtzMunich

Now it is official, Endocrine Regulatory Genomics Lab and Lickert Lab will collaborate on understanding mechanisms of autoimmune-endocrine cell interactions for insulin-producing beta cell protection! Thanks to Lorenzo for leading this great project and CaixaResearch for funding 😀🎉🍾