Great to see this research published, led by University of Exeter & King's College London - Young people could be spared from going blind by new genetic risk tool that could also help diagnose #MS earlier. Read the full story: bit.ly/42XKp9t

Pavel Loginovic Nature Communications Dr Tas Braithwaite FinnGen Feiyi Wang Geisinger Research This "Summer Project" turned into a beautiful piece of work by Pavel Loginovic Dr Tas Braithwaite and team, thanks also to Kris and the team in helping develop a web app mspredictor.com, It highlights the potential to leverage genetics in predicting MS. National MS Society Exeter Med School

Out today Nature Communications Thanks to Royal College of Ophthalmologists Fight for Sight Guy's and St Thomas' School of Immunology & Microbial Sciences School of Life Course & Population Sciences UK Biobank for supporting this research! Congratulations Pavel Loginovic and collaborators for a huge international undertaking

Fantastic paper in Nature Communications from Dr Tas Braithwaite and colleagues at King's College London and Exeter Med School showing how #mutliplesclerosis genetic risk scores can help predict whether people experiencing optic neuritis will go on to be diagnosed with MS nature.com/articles/s4146…

Appreciate your interest in our study! That’s correct for UKBiobank (41% of the highest risk developed MS), but was ↑ in FinnGen & ↓ in Geisinger. Lowest risk (4% in UKB) might also be helpful to ophthalmologists managing ON acutely, where knowing likely non-MS-ON is important

Baranzini: To understand MS, SPOKE database of 40 million items can be used. SPOKE now being used for drug development. Network signature in the form of bar codes can be created for individual patients. Can actually predict who will get MS in 3 years (83% accuracy). #ACTRIMS2024

Optic neuritis is a condition that affects the eye and your vision. It is caused by inflammation of the optic nerve. New genetics research could help diagnose MS earlier for people with optic neuritis. Find out more: mssoc.uk/3T0gV61

MOGAD (Myelin Oligodendrocyte Glycoprotein Associated Disease) youtu.be/V2fNC9SV2HU?si…

From University of Exeter King's College London: beautiful study examining genetic risk scores for predicting multiple sclerosis in people with optic neuritis. Pavel Loginovic Feiyi Wang Lauric Ferrat Harry Green 🇪🇺 Mike Weedon Richard Oram Dr Tas Braithwaite Nature Communications: go.nature.com/48CjTTZ

Exciting new @nature paper identifying new molecular pathways involved in smouldering MS. Congrats to the authors Cory Willis L Peruzzotti-Jametti Grzegorz Krzak Pluchino lab - Regenerative Neuroimmunology

New PGS to predict multiple sclerosis (MS) risk in individuals with optic neuritis: pgscatalog.org/publication/PG… Thanks to Pavel Loginovic Richard Oram Mike Weedon for sharing! Share your scores at pgscatalog.org/submit

T1D and other autoimmune diseases (AIDs) co-occur in families. How parental AIDs impact T1D risk in offspring and how much of the familial risk is explained by HLA and non-HLA variants? 👩🏻‍🦱🧔🏻‍♂️👶🏻 Find out more from this thread 🧵 and our new preprint ⬇️!medrxiv.org/content/10.110…

Mark Translational Brain Science Research Birmingham UK Sally Abbott IIH UK Neurology Trainees NANSIG (Neurology and Neurosurgery Interest Group) NANOS EUNOSsociety healthy weight or those living without obesity do not commonly get #IIH. When they do their outcomes are similar to those living with obesity at baseline tandfonline.com/doi/full/10.10…

#EUNOS2024 Have you not yet registered for EUNOS 2024? Make sure to register today, using this link: eunos2024.org/registration/! Please note, the deadline for the regular registration fee is 20 May. UKNOSoc EUNOSsociety Neurology Trainees 3rd -6th June in Rotterdam

So many great events are lined up for the ones fascinated by #neuroophthalmology Starting with #EUNOS2024, followed by course in Palermoand #opticneuropathy day in Cambridge. You still can join #NANOS2024 on demand online!

There are distinct atrophy patterns in retinal small vessels in people with #MultipleSclerosis, as from different underlying pathology. OCT-angiography study from TU München ▶️ journals.sagepub.com/doi/10.1177/13…

#EUNOS2024 did #covid19 or vaccination for c-19 change the incidence of #opticneuritis in the U.K. Dr Tas Braithwaite great data Applied Health Sciences NANOS EUNOSsociety UKNOSoc … no change. Importance of #bigdata this also reflects big data elsewhere

Sad to hear the passing of Akira Endo who discovered the statins. During his childhood, Akira was inspired by Alexander Fleming and his discovery of Penicillin from fungal mold. Fate would have it, he ended up discovering the second most important medicine of the century in

📣 NANSIG is thrilled to introduce our National Committee for 2024/25! 📣 We are excited and honored to have been selected, and we can't wait to bring you incredible events and resources!