Our latest paper exploring how MYC-MAX and CLOCK-BMAL1 engage with chromatinized E-boxes is out nature: rdcu.be/df8qh. We thank all the collaborators for their valuable contributions! Jerome Menet @partchlab Beat Fierz Schübeler Lab @johannes_zuber, Becker lab & Liu lab

How about some structural circadian biology to end the week? @partchlab @labthoma Lisa Stoos demonstrate how CLOCK:BMAL1 binds DNA in the context of histones, and show some rather elegant and surprising molecular interactions: nature.com/articles/s4158…

We are happy to share our latest work about the E3 ligase UBR5: Two manuscripts Cell Press! bit.ly/43vM7gJ bit.ly/3DnmRyI The result of fantastic collaborative efforts with the Ebert and Rapé Lab. Thanks to the many contributing authors! #cryoEM #ubiquitin

Excited to share our latest preprint. Lead by Mario (@marioiurlaro) and Francesca we deleted the main subcomplexes of the ISWI remodeler family. Key finding is that NURF (via BPTF) is required for creating open chromatin around CTCF sites. biorxiv.org/cgi/content/sh… 1/8

Check out our latest review on Pioneer Transcription Factors (TFs) by Manuel Carminati, Luca Vecchia, and Lisa Stoos in Current Opinion in Structural Biology Current Opinion/Research in Structural Biology! Read it here: doi.org/10.1016/j.sbi.…

Wouldn’t it be great to test how individual transcription factors engage with their motif in the nucleus? We tried exactly that in a study lead by Ralph (Ralph Grand) and Marco (Marco Pregnolato) now out in Molecular Cell authors.elsevier.com/sd/article/S10…. 1/7

I'm excited to share that I received a poster prize at the EMBL Transcription and Chromatin conference! Grateful for the opportunity and recognition!☺️ #EMBL2024

Mission accomplished✔️🎓 I recently defended my PhD thesis! Thanks a lot to my PhD supervisor Nicolas Thomä, my committee members Lori Passmore and Dirk Schübeler, the lab members and all the people who contributed during the journey!🎉🧬 Thomä Lab Lori Passmore Schübeler Lab